Growth/differentiation factor 2 (GDF-2) (Bone morphogenetic protein 9) (BMP-9)
1_MCPGA 6_ LWVAL 11_ PLLSL 16_ LAGSL 21_ QGKPL 26_ QSWGR 31_ GSAGG 36_ NAHSP 41_ LGVPG 46_ GGLPE 51_ HTFNL 56_ KMFLE 61_ NVKVD 66_ FLRSL 71_ NLSGV 76_ PSQDK 81_ TRVEP 86_ PQYMI 91_ DLYNR 96_ YTSDK 101_ STTPA 106_ SNIVR 111_ SFSME 116_ DAISI 121_ TATED 126_ FPFQK 131_ HILLF 136_ NISIP 141_ RHEQI 146_ TRAEL 151_ RLYVS 156_ CQNHV 161_ DPSHD 166_ LKGSV 171_ VIYDV 176_ LDGTD 181_ AWDSA 186_ TETKT 191_ FLVSQ 196_ DIQDE 201_ GWETL 206_ EVSSA 211_ VKRWV 216_ RSDST 221_ KSKNK 226_ LEVTV 231_ ESHRK 236_ GCDTL 241_ DISVP 246_ PGSRN 251_ LPFFV 256_ VFSND 261_ HSSGT 266_ KETRL 271_ ELREM 276_ ISHEQ 281_ ESVLK 286_ KLSKD 291_ GSTEA 296_ GESSH 301_ EEDTD 306_ GHVAA 311_ GSTLA 316_ RRKRS 321_ AGAGS 326_ HCQKT 331_ SLRVN 336_ FEDIG 341_ WDSWI 346_ IAPKE 351_ YEAYE 356_ CKGGC 361_ FFPLA 366_ DDVTP 371_ TKHAI 376_ VQTLV 381_ HLKFP 386_ TKVGK 391_ ACCVP 396_ TKLSP 401_ ISVLY 406_ KDDMG 411_ VPTLK 416_ YHYEG 421_MSVAE
1: Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG