Dickkopf-like protein 1 (Cancer/testis antigen 34) (CT34) (Protein soggy-1) (SGY-1)
1_MGEAS 6_ PPAPA 11_ RRHLL 16_ VLLLL 21_ LSTLV 26_ IPSAA 31_ APIHD 36_ ADAQE 41_ SSLGL 46_ TGLQS 51_ LLQGF 56_ SRLFL 61_ KGNLL 66_ RGIDS 71_ LFSAP 76_ MDFRG 81_ LPGNY 86_ HKEEN 91_ QEHQL 96_ GNNTL 101_ SSHLQ 106_ IDKMT 111_ DNKTG 116_ EVLIS 121_ ENVVA 126_ SIQPA 131_ EGSFE 136_ GDLKV 141_ PRMEE 146_ KEALV 151_ PIQKA 156_ TDSFH 161_ TELHP 166_ RVAFW 171_ IIKLP 176_ RRRSH 181_ QDALE 186_ GGHWL 191_ SEKRH 196_ RLQAI 201_ RDGLR 206_ KGTHK 211_ DVLEE 216_ GTESS 221_ SHSRL 226_ SPRKT 231_ HLLYI 236_LRPSR
1: Involved in fertilization by facilitating sperm penetration of the zona pellucida. May promote spermatocyte apoptosis, thereby limiting sperm production. In adults, may reduce testosterone synthesis in Leydig cells. Is not essential either for development or fertility