F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5)
1_MSPVF 6_ PMLTV 11_ LTMFY 16_ YICLR 21_ RRART 26_ ATRGE 31_ MMNTH 36_ RAIES 41_ NSQTS 46_ PLNAE 51_ VVQYA 56_ KEVVD 61_ FSSHY 66_ GSENS 71_ MSYTM 76_ WNLAG 81_ VPNVF 86_ PSSGD 91_ FTQTA 96_ VFRTY 101_ GTWWD 106_ QCPSA 111_ SLPFK 116_ RTPPN 121_ FQSQD 126_ YVELT 131_ FEQQV 136_ YPTAV 141_ HVLET 146_ YHPGA 151_ VIRIL 156_ ACSAN 161_ PYSPN 166_ PPAEV 171_ RWEIL 176_ WSERP 181_ TKVNA 186_ SQARQ 191_ FKPCI 196_ KQINF 201_ PTNLI 206_ RLEVN 211_ SSLLE 216_ YYTEL 221_ DAVVL 226_ HGVKD 231_ KPVLS 236_ LKTSL 241_ IDMND 246_ IEDDA 251_ YAEKD 256_ GCGMD 261_ SLNKK 266_ FSSAV 271_ LGEGP 276_ NNGYF 281_ DKLPY 286_ ELIQL 291_ ILNHL 296_ TLPDL 301_ CRLAQ 306_ TCKLL 311_ SQHCC 316_ DPLQY 321_ IHLNL 326_ QPYWA 331_ KLDDT 336_ SLEFL 341_ QSRCT 346_ LVQWL 351_ NLSWT 356_ GNRGF 361_ ISVAG 366_ FSRFL 371_ KVCGS 376_ ELVRL 381_ ELSCS 386_ HFLNE 391_ TCLEV 396_ ISEMC 401_ PNLQA 406_ LNLSS 411_ CDKLP 416_ PQAFN 421_ HIAKL 426_ CSLKR 431_ LVLYR 436_ TKVEQ 441_ TALLS 446_ ILNFC 451_ SELQH 456_ LSLGS 461_ CVMIE 466_ DYDVI 471_ ASMIG 476_ AKCKK 481_ LRTLD 486_ LWRCK 491_ NITEN 496_ GIAEL 501_ ASGCP 506_ LLEEL 511_ DLGWC 516_ PTLQS 521_ STGCF 526_ TRLAH 531_ QLPNL 536_ QKLFL 541_ TANRS 546_ VCDTD 551_ IDELA 556_ CNCTR 561_ LQQLD 566_ ILGTR 571_ MVSPA 576_ SLRKL 581_ LESCK 586_ DLSLL 591_ DVSFC 596_ SQIDN 601_ RAVLE 606_ LNASF 611_ PKVFI 616_KKSFT
1: Substrate-recognition component of the mitochondria-localized SCF-FBXL4 ubiquitin E3 ligase complex that plays a role in the restriction of mitophagy by controlling the degradation of BNIP3 and NIX mitophagy receptors (PubMed:36896912, PubMed:38992176). Rescues also mitochondrial injury through reverting hyperactivation of DRP1-mediated mitochondrial fission (By similarity)