Isobutyryl-CoA dehydrogenase, mitochondrial (IBDH) (EC 1.3.8.-) (Activator-recruited cofactor 42 kDa component) (ARC42) (Acyl-CoA dehydrogenase family member 8) (ACAD-8)
1_MLWSG 6_ CRRFG 11_ ARLGC 16_ LPGGL 21_ RVLVQ 26_ TGHRS 31_ LTSCI 36_ DPSMG 41_ LNEEQ 46_ KEFQK 51_ VAFDF 56_ AAREM 61_ APNMA 66_ EWDQK 71_ ELFPV 76_ DVMRK 81_ AAQLG 86_ FGGVY 91_ IQTDV 96_ GGSGL 101_ SRLDT 106_ SVIFE 111_ ALATG 116_ CTSTT 121_ AYISI 126_ HNMCA 131_ WMIDS 136_ FGNEE 141_ QRHKF 146_ CPPLC 151_ TMEKF 156_ ASYCL 161_ TEPGS 166_ GSDAA 171_ SLLTS 176_ AKKQG 181_ DHYIL 186_ NGSKA 191_ FISGA 196_ GESDI 201_ YVVMC 206_ RTGGP 211_ GPKGI 216_ SCIVV 221_ EKGTP 226_ GLSFG 231_ KKEKK 236_ VGWNS 241_ QPTRA 246_ VIFED 251_ CAVPV 256_ ANRIG 261_ SEGQG 266_ FLIAV 271_ RGLNG 276_ GRINI 281_ ASCSL 286_ GAAHA 291_ SVILT 296_ RDHLN 301_ VRKQF 306_ GEPLA 311_ SNQYL 316_ QFTLA 321_ DMATR 326_ LVAAR 331_ LMVRN 336_ AAVAL 341_ QEERK 346_ DAVAL 351_ CSMAK 356_ LFATD 361_ ECFAI 366_ CNQAL 371_ QMHGG 376_ YGYLK 381_ DYAVQ 386_ QYVRD 391_ SRVHQ 396_ ILEGS 401_ NEVMR 406_ILISR
1: Isobutyryl-CoA dehydrogenase which catalyzes the conversion of 2-methylpropanoyl-CoA to (2E)-2-methylpropenoyl-CoA in the valine catabolic pathway (PubMed:11013134, PubMed:12359132, PubMed:16857760). To a lesser extent, also able to catalyze the oxidation of (2S)-2-methylbutanoyl-CoA (PubMed:11013134, PubMed:12359132)