Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 2)
1_MPPAT 6_ GGGLA 11_ ESELR 16_ PRRGR 21_ CGPQA 26_ ARAAG 31_ RDVAA 36_ EAVAR 41_ SPKRP 46_ AWGSR 51_ RFEAV 56_ GWWAL 61_ LALVT 66_ LLSFA 71_ TRFHR 76_ LDEPP 81_ HICWD 86_ ETHFG 91_ KMGSY 96_ YINRT 101_ FFFDV 106_ HPPLG 111_ KMLIG 116_ LAGYL 121_ SGYDG 126_ TFLFQ 131_ KPGDK 136_ YEHHS 141_ YMGMR 146_ GFCAF 151_ LGSWL 156_ VPFAY 161_ LTVLD 166_ LSKSL 171_ SAALL 176_ TAALL 181_ TFDTG 186_ CLTLS 191_ QYILL 196_ DPILM 201_ FFIMA 206_ AMLSM 211_ VKYNS 216_ CADRP 221_ FSAPW 226_ WFWLS 231_ LTGVS 236_ LAGAL 241_ GVKFV 246_ GLFII 251_ LQVGL 256_ NTIAD 261_ LWYLF 266_ GDLSL 271_ SLVTV 276_ GKHLT 281_ ARVLC 286_ LIVLP 291_ LALYT 296_ ATFAV 301_ HFMVL 306_ SKSGP 311_ GDGFF 316_ SSAFQ 321_ ARLSG 326_ NNLHN 331_ ASIPE 336_ HLAYG 341_ SVITV 346_ KNLRM 351_ AIGYL 356_ HSHRH 361_ LYPEG 366_ IGARQ 371_ QQVTT 376_ YLHKD 381_ YNNLW 386_ IIKKH 391_ NTNSD 396_ PLDPS 401_ FPVEF 406_ VRHGD 411_ IIRLE 416_ HKETS 421_ RNLHS 426_ HYHEA 431_ PMTRK 436_ HYQVT 441_ GYGIN 446_ GTGDS 451_ NDFWR 456_ IEVVN 461_ RKFGN 466_ RIKVL 471_ RSRIR 476_ FIHLV 481_ TGCVL 486_ GSSGK 491_ VLPKW 496_ GWEQL 501_ EVTCT 506_ PYLKE 511_ TLNSI 516_ WNVED 521_ HINPK 526_ LPNIS 531_ LDVLQ 536_ PSFPE 541_ ILLES 546_ HMVMI 551_ RGNSG 556_ LKPKD 561_ NEFTS 566_ KPWHW 571_ PINYQ 576_ GLRFS 581_ GVNDT 586_ DFRVY 591_ LLGNP 596_ VVWWL 601_ NLLSI 606_ ALYLL 611_ SGSII 616_ AVAMQ 621_ RGARL 626_ PAEVA 631_ GLSQV 636_ LLRGG 641_ GQVLL 646_ GWTLH 651_ YFPFF 656_ LMGRV 661_ LYFHH 666_ YFPAM 671_ LFSSM 676_ LTGIL 681_ WDTLL 686_ RLCAW 691_ GLASW 696_ PLARG 701_ IHVAG 706_ ILSLL 711_ LGTAY 716_ SFYLF 721_ HPLAY 726_ GMVGP 731_ LAQDP 736_ QSPMA 741_GLRWL
1: Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient (PubMed:14699049, PubMed:28512129). Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins (PubMed:28512129)