Proteasome activator complex subunit 2 (11S regulator complex subunit beta) (REG-beta) (Activator of multicatalytic protease subunit 2) (Proteasome activator 28 subunit beta) (PA28b) (PA28beta)
1_MAKPC 6_ GVRLS 11_ GEARK 16_ QVEVF 21_ RQNLF 26_ QEAEE 31_ FLYRF 36_ LPQKI 41_ IYLNQ 46_ LLQED 51_ SLNVA 56_ DLTSL 61_ RAPLD 66_ IPIPD 71_ PPPKD 76_ DEMET 81_ DKQEK 86_ KEVHK 91_ CGFLP 96_ GNEKV 101_ LSLLA 106_ LVKPE 111_ VWTLK 116_ EKCIL 121_ VITWI 126_ QHLIP 131_ KIEDG 136_ NDFGV 141_ AIQEK 146_ VLERV 151_ NAVKT 156_ KVEAF 161_ QTTIS 166_ KYFSE 171_ RGDAV 176_ AKASK 181_ ETHVM 186_ DYRAL 191_ VHERD 196_ EAAYG 201_ ELRAM 206_ VLDLR 211_ AFYAE 216_ LYHII 221_ SSNLE 226_ KIVNP 231_KGEEK
1: Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome