Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10)
1_MKVHM 6_ HTKFC 11_ LICLL 16_ TFIFH 21_ HCNHC 26_ HEEHD 31_ HGPEA 36_ LHRQH 41_ RGMTE 46_ LEPSK 51_ FSKQA 56_ AENEK 61_ KYYIE 66_ KLFER 71_ YGENG 76_ RLSFF 81_ GLEKL 86_ LTNLG 91_ LGERK 96_ VVEIN 101_ HEDLG 106_ HDHVS 111_ HLDIL 116_ AVQEG 121_ KHFHS 126_ HNHQH 131_ SHNHL 136_ NSENQ 141_ TVTSV 146_ STKRN 151_ HKCDP 156_ EKETV 161_ EVSVK 166_ SDDKH 171_ MHDHN 176_ HRLRH 181_ HHRLH 186_ HHLDH 191_ NNTHH 196_ FHNDS 201_ ITPSE 206_ RGEPS 211_ NEPST 216_ ETNKT 221_ QEQSD 226_ VKLPK 231_ GKRKK 236_ KGRKS 241_ NENSE 246_ VITPG 251_ FPPNH 256_ DQGEQ 261_ YEHNR 266_ VHKPD 271_ RVHNP 276_ GHSHV 281_ HLPER 286_ NGHDP 291_ GRGHQ 296_ DLDPD 301_ NEGEL 306_ RHTRK 311_ REAPH 316_ VKNNA 321_ IISLR 326_ KDLNE 331_ DDHHH 336_ ECLNV 341_ TQLLK 346_ YYGHG 351_ ANSPI 356_ STDLF 361_ TYLCP 366_ ALLYQ 371_ IDSRL 376_ CIEHF 381_ DKLLV 386_ EDINK 391_ DKNLV 396_ PEDEA 401_ NIGAS 406_ AWICG 411_ IISIT 416_ VISLL 421_ SLLGV 426_ ILVPI 431_ INQGC 436_ FKFLL 441_ TFLVA 446_ LAVGT 451_ MSGDA 456_ LLHLL 461_ PHSQG 466_ GHDHS 471_ HQHAH 476_ GHGHS 481_ HGHES 486_ NKFLE 491_ EYDAV 496_ LKGLV 501_ ALGGI 506_ YLLFI 511_ IEHCI 516_ RMFKH 521_ YKQQR 526_ GKQKW 531_ FMKQN 536_ TEEST 541_ IGRKL 546_ SDHKL 551_ NNTPD 556_ SDWLQ 561_ LKPLA 566_ GTDDS 571_ VVSED 576_ RLNET 581_ ELTDL 586_ EGQQE 591_ SPPKN 596_ YLCIE 601_ EEKII 606_ DHSHS 611_ DGLHT 616_ IHEHD 621_ LHAAA 626_ HNHHG 631_ ENKTV 636_ LRKHN 641_ HQWHH 646_ KHSHH 651_ SHGPC 656_ HSGSD 661_ LKETG 666_ IANIA 671_ WMVIM 676_ GDGIH 681_ NFSDG 686_ LAIGA 691_ AFSAG 696_ LTGGI 701_ STSIA 706_ VFCHE 711_ LPHEL 716_ GDFAV 721_ LLKAG 726_ MTVKQ 731_ AIVYN 736_ LLSAM 741_ MAYIG 746_ MLIGT 751_ AVGQY 756_ ANNIT 761_ LWIFA 766_ VTAGM 771_ FLYVA 776_ LVDML 781_ PEMLH 786_ GDGDN 791_ EEHGF 796_ CPVGQ 801_ FILQN 806_ LGLLF 811_ GFAIM 816_ LVIAL 821_ YEDKI 826_VFDIQ
1: Zinc-influx transporter (PubMed:17359283, PubMed:27274087, PubMed:30520657). When associated with SLC39A6, the heterodimer formed by SLC39A10 and SLC39A6 mediates cellular zinc uptake to trigger cells to undergo epithelial-to-mesenchymal transition (EMT) (PubMed:23186163). SLC39A10-SLC39A6 heterodimers play also an essentiel role in initiating mitosis by importing zinc into cells to initiate a pathway resulting in the onset of mitosis (PubMed:32797246). Plays an important for both mature B-cell maintenance and humoral immune responses (By similarity). When associated with SLC39A10, the heterodimer controls NCAM1 phosphorylation and integration into focal adhesion complexes during EMT (By similarity)