Protein NDRG2 (N-myc downstream-regulated gene 2 protein) (Protein Syld709613)
1_MAELQ 6_ EVQIT 11_ EEKPL 16_ LPGQT 21_ PEAAK 26_ EAELA 31_ ARILL 36_ DQGQT 41_ HSVET 46_ PYGSV 51_ TFTVY 56_ GTPKP 61_ KRPAI 66_ LTYHD 71_ VGLNY 76_ KSCFQ 81_ PLFQF 86_ EDMQE 91_ IIQNF 96_ VRVHV 101_ DAPGM 106_ EEGAP 111_ VFPLG 116_ YQYPS 121_ LDQLA 126_ DMIPC 131_ VLQYL 136_ NFSTI 141_ IGVGV 146_ GAGAY 151_ ILARY 156_ ALNHP 161_ DTVEG 166_ LVLIN 171_ IDPNA 176_ KGWMD 181_ WAAHK 186_ LTGLT 191_ SSIPE 196_ MILGH 201_ LFSQE 206_ ELSGN 211_ SELIQ 216_ KYRNI 221_ ITHAP 226_ NLDNI 231_ ELYWN 236_ SYNNR 241_ RDLNF 246_ ERGGD 251_ ITLRC 256_ PVMLV 261_ VGDQA 266_ PHEDA 271_ VVECN 276_ SKLDP 281_ TQTSF 286_ LKMAD 291_ SGGQP 296_ QLTQP 301_ GKLTE 306_ AFKYF 311_ LQGMG 316_ YMASS 321_ CMTRL 326_ SRSRT 331_ ASLTS 336_ AASVD 341_ GNRSR 346_ SRTLS 351_ QSSES 356_ GTLSS 361_ GPPGH 366_TMEVS
1: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation