Gamma-aminobutyric acid receptor subunit theta (GABA(A) receptor subunit theta)
1_MGIRG 6_ MLRAA 11_ VILLL 16_ IRTWL 21_ AEGNY 26_ PSPIP 31_ KFHFE 36_ FSSAV 41_ PEVVL 46_ NLFNC 51_ KNCAN 56_ EAVVQ 61_ KILDR 66_ VLSRY 71_ DVRLR 76_ PNFGG 81_ APVPV 86_ RISIY 91_ VTSIE 96_ QISEM 101_ NMDYT 106_ ITMFF 111_ HQTWK 116_ DSRLA 121_ YYETT 126_ LNLTL 131_ DYRMH 136_ EKLWV 141_ PDCYF 146_ LNSKD 151_ AFVHD 156_ VTVEN 161_ RVFQL 166_ HPDGT 171_ VRYGI 176_ RLTTT 181_ AACSL 186_ DLHKF 191_ PMDKQ 196_ ACNLV 201_ VESYG 206_ YTVED 211_ IILFW 216_ DDNGN 221_ AIHMT 226_ EELHI 231_ PQFTF 236_ LGRTI 241_ TSKEV 246_ YFYTG 251_ SYIRL 256_ ILKFQ 261_ VQREV 266_ NSYLV 271_ QVYWP 276_ TVLTT 281_ ITSWI 286_ SFWMN 291_ YDSSA 296_ ARVTI 301_ GLTSM 306_ LILTT 311_ IDSHL 316_ RDKLP 321_ NISCI 326_ KAIDI 331_ YILVC 336_ LFFVF 341_ LSLLE 346_ YVYIN 351_ YLFYS 356_ RGPRR 361_ QPRRH 366_ RRPRR 371_ VIARY 376_ RYQQV 381_ VVGNV 386_ QDGLI 391_ NVEDG 396_ VSSLP 401_ ITPAQ 406_ APLAS 411_ PESLG 416_ SLTST 421_ SEQAQ 426_ LATSE 431_ SLSPL 436_ TSLSG 441_ QAPLA 446_ TGESL 451_ SDLPS 456_ TSEQA 461_ RHSYG 466_ VRFNG 471_ FQADD 476_ SIIPT 481_ EIRNR 486_ VEAHG 491_ HGVTH 496_ DHEDS 501_ NESLS 506_ SDERH 511_ GHGPS 516_ GKPML 521_ HHGEK 526_ GVQEA 531_ GWDLD 536_ DNNDK 541_ SDCLA 546_ IKEQF 551_ KCDTN 556_ STWGL 561_ NDDEL 566_ MAHGQ 571_ EKDSS 576_ SESED 581_ SCPPS 586_ PGCSF 591_ TEGFS 596_ FDLFN 601_ PDYVP 606_ KVDKW 611_ SRFLF 616_ PLAFG 621_ LFNIV 626_YWVYH
1: Theta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790, PubMed:16412217). GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interfaces (By similarity). When activated by GABA, GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient (PubMed:10449790, PubMed:16412217)