Tumor necrosis factor receptor superfamily member EDAR (Anhidrotic ectodysplasin receptor 1) (Downless homolog) (EDA-A1 receptor) (Ectodermal dysplasia receptor) (Ectodysplasin-A receptor)
1_MAHVG 6_ DCTQT 11_ PWLPV 16_ LVVSL 21_ MCSAR 26_ AEYSN 31_ CGENE 36_ YYNQT 41_ TGLCQ 46_ ECPPC 51_ GPGEE 56_ PYLSC 61_ GYGTK 66_ DEDYG 71_ CVPCP 76_ AEKFS 81_ KGGYQ 86_ ICRRH 91_ KDCEG 96_ FFRAT 101_ VLTPG 106_ DMEND 111_ AECGP 116_ CLPGY 121_ YMLEN 126_ RPRNI 131_ YGMVC 136_ YSCLL 141_ APPNT 146_ KECVG 151_ ATSGA 156_ SANFP 161_ GTSGS 166_ STLSP 171_ FQHAH 176_ KELSG 181_ QGHLA 186_ TALII 191_ AMSTI 196_ FIMAI 201_ AIVLI 206_ IMFYI 211_ LKTKP 216_ SAPAC 221_ CTSHP 226_ GKSVE 231_ AQVSK 236_ DEEKK 241_ EAPDN 246_ VVMFS 251_ EKDEF 256_ EKLTA 261_ TPAKP 266_ TKSEN 271_ DASSE 276_ NEQLL 281_ SRSVD 286_ SDEEP 291_ APDKQ 296_ GSPEL 301_ CLLSL 306_ VHLAR 311_ EKSAT 316_ SNKSA 321_ GIQSR 326_ RKKIL 331_ DVYAN 336_ VCGVV 341_ EGLSP 346_ TELPF 351_ DCLEK 356_ TSRML 361_ SSTYN 366_ SEKAV 371_ VKTWR 376_ HLAES 381_ FGLKR 386_ DEIGG 391_ MTDGM 396_ QLFDR 401_ ISTAG 406_ YSIPE 411_ LLTKL 416_ VQIER 421_ LDAVE 426_ SLCAD 431_ ILEWA 436_ GVVPP 441_ASQPH
1: Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death