Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2)
1_MEEVR 6_ CPEHG 11_ TFCFL 16_ KTGVR 21_ DGPNK 26_ GKSFY 31_ VCRAD 36_ TCSFV 41_ RATDI 46_ PVSHC 51_ LLHED 56_ FVVEL 61_ QGLLL 66_ PQDKK 71_ EYRLF 76_ FRCIR 81_ SKAEG 86_ KRWCG 91_ SIPWQ 96_ DPDSK 101_ EHSVS 106_ NKSQH 111_ ASETF 116_ HHSSN 121_ WLRNP 126_ FKVLD 131_ KNQEP 136_ ALWKQ 141_ LIKGE 146_ GEEKK 151_ ADKKQ 156_ REKGD 161_ QLFDQ 166_ KKEQK 171_ PEMME 176_ KDLSS 181_ GLVPK 186_ KKQSV 191_ VQEKK 196_ QEEGA 201_ EIQCE 206_ AETGG 211_ THKRD 216_ FSEIK 221_ SQQCQ 226_ GNELT 231_ RPSAS 236_ SQEKS 241_ SGKSQ 246_ DVQRE 251_ SEPLR 256_ EKVTQ 261_ LLPQN 266_ VHSHN 271_ SISKP 276_ QKGGP 281_ LNKEY 286_ TNWEA 291_ KETKA 296_ KDGPS 301_ IQATQ 306_ KSLPQ 311_ GHFQE 316_ RPETH 321_ SVPAP 326_ GGPAA 331_ QAAPA 336_ APGLS 341_ LGEGR 346_ EAATS 351_ SDDEE 356_ EDDVV 361_ FVSSK 366_ PGSPL 371_ LFDST 376_ LDLET 381_ KENLQ 386_ FPDRS 391_ VQRKV 396_ SPASG 401_ VSKKV 406_ EPSDP 411_ VARRV 416_ YLTTQ 421_ LKQKK 426_ STLAS 431_ VNIQA 436_ LPDKG 441_ QKLIK 446_ QIQEL 451_ EEVLS 456_ GLTLS 461_ PEQGT 466_ NEKSN 471_ SQVPQ 476_ QSHFT 481_ KTTTG 486_ PPHLV 491_ PPQPL 496_ PRRGT 501_ QPVGS 506_ LELKS 511_ ACQVT 516_ AGGSS 521_ QCYRG 526_ HTNQD 531_ HVHAV 536_ WKITS 541_ EAIGQ 546_ LHRSL 551_ ESCPG 556_ ETVVA 561_ EDPAG 566_ LKVPL 571_ LLHQK 576_ QALAW 581_ LLWRE 586_ SQKPQ 591_ GGILA 596_ DDMGL 601_ GKTLT 606_ MIALI 611_ LTQKN 616_ QEKKE 621_ EKEKS 626_ TALTW 631_ LSKDD 636_ SCDFT 641_ SHGTL 646_ IICPA 651_ SLIHH 656_ WKNEV 661_ EKRVN 666_ SNKLR 671_ VYLYH 676_ GPNRD 681_ SRARV 686_ LSTYD 691_ IVITT 696_ YSLVA 701_ KEIPT 706_ NKQEA 711_ EIPGA 716_ NLNVE 721_ GTSTP 726_ LLRIA 731_ WARII 736_ LDEAH 741_ NVKNP 746_ RVQTS 751_ IAVCK 756_ LQACA 761_ RWAVT 766_ GTPIQ 771_ NNLLD 776_ MYSLL 781_ KFLRC 786_ SPFDE 791_ FNLWR 796_ SQVDN 801_ GSKKG 806_ GERLS 811_ ILTKS 816_ LLLRR 821_ TKDQL 826_ DSTGR 831_ PLVIL 836_ PQRKF 841_ QLHHL 846_ KLSED 851_ EETVY 856_ NVFFA 861_ RSRSA 866_ LQSYL 871_ KRHES 876_ RGNQS 881_ GRSPN 886_ NPFSR 891_ VALEF 896_ GSEEP 901_ RHSEA 906_ ADSPR 911_ SSTVH 916_ ILSQL 921_ LRLRQ 926_ CCCHL 931_ SLLKS 936_ ALDPM 941_ ELKGE 946_ GLVLS 951_ LEEQL 956_ SALTL 961_ SELRD 966_ SEPSS 971_ TVSLN 976_ GTFFK 981_ MELFE 986_ GMRES 991_ TKISS 996_ LLAEL 1001_ EAIQR 1006_ NSASQ 1011_ KSVIV 1016_ SQWTN 1021_ MLKVV 1026_ ALHLK 1031_ KHGLT 1036_ YATID 1041_ GSVNP 1046_ KQRMD 1051_ LVEAF 1056_ NHSRG 1061_ PQVML 1066_ ISLLA 1071_ GGVGL 1076_ NLTGG 1081_ NHLFL 1086_ LDMHW 1091_ NPSLE 1096_ DQACD 1101_ RIYRV 1106_ GQQKD 1111_ VVIHR 1116_ FVCEG 1121_ TVEEK 1126_ ILQLQ 1131_ EKKKD 1136_ LAKQV 1141_ LSGSG 1146_ ESVTK 1151_ LTLAD 1156_LRVLF
1: DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing