Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B)
1_MENSH 6_ PPHHH 11_ HQQPP 16_ PQPGP 21_ SGERR 26_ NHHWR 31_ SYKLM 36_ IDPAL 41_ KKGHH 46_ KLYRY 51_ DGQHF 56_ SLAMS 61_ SNRPV 66_ EIVED 71_ PRVVG 76_ IWTKN 81_ KELEL 86_ SVPKF 91_ KIDEF 96_ YVGPV 101_ PPKQV 106_ TFAKL 111_ NDNIR 116_ ENFLR 121_ DMCKK 126_ YGEVE 131_ EVEIL 136_ YNPKT 141_ KKHLG 146_ IAKVV 151_ FATVR 156_ GAKDA 161_ VQHLH 166_ STSVM 171_ GNIIH 176_ VELDT 181_ KGETR 186_ MRFYE 191_ LLVTG 196_ RYTPQ 201_ TLPVG 206_ ELDAV 211_ SPIVN 216_ ETLQL 221_ SDALK 226_ RLKDG 231_ GLSAG 236_ CGSGS 241_ SSVTP 246_ NSGGT 251_ PFSQD 256_ TAYSS 261_ CRLDT 266_ PNSYG 271_ QGTPL 276_ TPRLG 281_ TPFSQ 286_ DSSYS 291_ SRQPT 296_ PSYLF 301_ SQDPA 306_ VTFKA 311_ RRHES 316_ KFTDA 321_ YNRRH 326_ EHHYV 331_ HNSPA 336_ VTAVA 341_ GATAA 346_ FRGSS 351_ DLPFG 356_ AVGGT 361_ GGSSG 366_ PPFKA 371_ QPQDS 376_ ATFAH 381_ TPPPA 386_ QATPA 391_ PGFKS 396_ AFSPY 401_ QTPVA 406_ HFPPP 411_ PEEPT 416_ ATAAF 421_ GARDS 426_ GEFRR 431_ APAPP 436_ PLPPA 441_ EPLAK 446_ EKPGT 451_ PPGPP 456_ PPDTN 461_ SMELG 466_ GRPTF 471_ GWSPE 476_ PCDSP 481_ GTPTL 486_ ESSPA 491_ GPEKP 496_ HDSLD 501_ SRIEM 506_ LLKEQ 511_ RTKLL 516_ FLREP 521_ DSDTE 526_ LQMEG 531_ SPISS 536_ SSSQL 541_ SPLAP 546_ FGTNS 551_ QPGFR 556_ GPTPP 561_ SSRPS 566_ STGLE 571_ DISPT 576_ PLPDS 581_ DEDEE 586_ LDLGL 591_ GPRPP 596_ PEPGP 601_ PDPAG 606_ LLSQT 611_ AEVAL 616_ DLVGD 621_ RTPTS 626_ EKMDE 631_ GQQSS 636_ GEDME 641_ ISDDE 646_ MPSAP 651_ ITSAD 656_ CPKPM 661_ VVTPG 666_ AAAVA 671_ APSVL 676_ APTLP 681_ LPPPP 686_ GFPPL 691_ PPPPP 696_ PPPPQ 701_ PGFPM 706_ PPPLP 711_ PPPPP 716_ PPPAH 721_ PAVTV 726_ PPPPL 731_ PAPPG 736_ VPPPP 741_ ILPPL 746_ PPFPP 751_ GLFPV 756_ MQVDM 761_ SHVLG 766_ GQWGG 771_ MPMSF 776_ QMQTQ 781_ VLSRL 786_ MTGQG 791_ ACPYP 796_ PFMAA 801_ AAAAA 806_ SAGLQ 811_ FVNLP 816_ PYRGP 821_ FSLSN 826_ SGPGR 831_ GQHWP 836_ PLPKF 841_ DPSVP 846_ PPGYM 851_ PRQED 856_ PHKAT 861_ VDGVL 866_ LVVLK 871_ ELKAI 876_ MKRDL 881_ NRKMV 886_ EVVAF 891_ RAFDE 896_ WWDKK 901_ ERMAK 906_ ASLTP 911_ VKSGE 916_ HKDED 921_ RPKPK 926_ DRIAS 931_ CLLES 936_ WGKGE 941_ GLGYE 946_ GLGLG 951_ IGLRG 956_ AIRLP 961_ SFKVK 966_ RKEPP 971_ DTTSS 976_ GDQKR 981_ LRPST 986_ SVDEE 991_ DEESE 996_ RERDR 1001_ DMADT 1006_ PCELA 1011_ KRDPK 1016_ GVGVR 1021_ RRPAR 1026_ PLELD 1031_ SGGEE 1036_ DEKES 1041_ LSASS 1046_ SSSAS 1051_ SSSGS 1056_ STTSP 1061_ SSSAS 1066_ DKEEE 1071_ QESTE 1076_ EEEEA 1081_ EEEEE 1086_ EEVPR 1091_ SQLSS 1096_ SSTSS 1101_ TSDKD 1106_ DDDDD 1111_ SDDRD 1116_ ESEND 1121_ DEDTA 1126_ LSEAS 1131_ EKDEG 1136_ DSDEE 1141_ ETVSI 1146_ VTSKA 1151_ EATSS 1156_ SESSE 1161_ SSEFE 1166_ SSSES 1171_ SPSSS 1176_ EDEEE 1181_ VVARE 1186_ EEEEE 1191_ EEEEM 1196_ VAEES 1201_ MASAG 1206_ PEDFE 1211_ QDGEE 1216_ AALAP 1221_ GAPAV 1226_ DSLGM 1231_ EEEVD 1236_ IETEA 1241_ VAPEE 1246_ RPSML 1251_ DEPPL 1256_ PVGVE 1261_ EPADS 1266_ REPPE 1271_ EPGLS 1276_ QEGAM 1281_ LLSPE 1286_ PPAKE 1291_ VEARP 1296_ PLSPE 1301_ RAPEH 1306_ DLEVE 1311_ PEPPM 1316_ MLPLP 1321_ LQPPL 1326_ PPPRP 1331_ PRPPS 1336_ PPPEP 1341_ ETTDA 1346_ SHPSV 1351_ PPEPL 1356_ AEDHP 1361_ PHTPG 1366_ LCGSL 1371_ AKSQS 1376_ TETVP 1381_ ATPGG 1386_ EPPLS 1391_ GGSSG 1396_ LSLSS 1401_ PQVPG 1406_ SPFSY 1411_ PAPSP 1416_ SLSSG 1421_ GLPRT 1426_ PGRDF 1431_ SFTPT 1436_ FSEPS 1441_ GPLLL 1446_ PVCPL 1451_ PTGRR 1456_ DERSG 1461_ PLASP 1466_ VLLET 1471_ GLPLP 1476_ LPLPL 1481_ PLPLA 1486_ LPAVL 1491_ RAQAR 1496_ APTPL 1501_ PPLLP 1506_ APLAS 1511_ CPPPM 1516_ KRKPG 1521_ RPRRS 1526_ PPSML 1531_ SLDGP 1536_ LVRPP 1541_ AGAAL 1546_ GRELL 1551_ LLPGQ 1556_ PQTPV 1561_ FPSTH 1566_ DPRTV 1571_ TLDFR 1576_ NAGIP 1581_ APPPP 1586_ LPPQP 1591_ PPPPP 1596_ PPPVE 1601_ PTKLP 1606_ FKELD 1611_ NQWPS 1616_ EAIPP 1621_ GPRGR 1626_ DEVTE 1631_ EYMEL 1636_ AKSRG 1641_ PWRRP 1646_ PKKRH 1651_ EDLVP 1656_ PAGSP 1661_ ELSPP 1666_ QPLFR 1671_ PRSEF 1676_ EEMTI 1681_ LYDIW 1686_ NGGID 1691_ EEDIR 1696_ FLCVT 1701_ YERLL 1706_ QQDNG 1711_ MDWLN 1716_ DTLWV 1721_ YHPST 1726_ SLSSA 1731_ KKKKR 1736_ DDGIR 1741_ EHVTG 1746_ CARSE 1751_ GFYTI 1756_ DKKDK 1761_ LRYLN 1766_ SSRAS 1771_ TDEPP 1776_ ADTQG 1781_ MSIPA 1786_ QPHAS 1791_ TRAGS 1796_ ERRSE 1801_ QRRLL 1806_ SSFTG 1811_ SCDSD 1816_ LLKFN 1821_ QLKFR 1826_ KKKLK 1831_ FCKSH 1836_ IHDWG 1841_ LFAME 1846_ PIAAD 1851_ EMVIE 1856_ YVGQN 1861_ IRQVI 1866_ ADMRE 1871_ KRYED 1876_ EGIGS 1881_ SYMFR 1886_ VDHDT 1891_ IIDAT 1896_ KCGNF 1901_ ARFIN 1906_ HSCNP 1911_ NCYAK 1916_ VITVE 1921_ SQKKI 1926_ VIYSK 1931_ QHINV 1936_ NEEIT 1941_ YDYKF 1946_ PIEDV 1951_ KIPCL 1956_ CGSEN 1961_CRGTL
1: Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism (PubMed:17355966, PubMed:25561738). Part of chromatin remodeling machinery, forms H3K4me1, H3K4me2 and H3K4me3 methylation marks at active chromatin sites where transcription and DNA repair take place (PubMed:17355966, PubMed:25561738). Plays an essential role in regulating the transcriptional programming of multipotent hematopoietic progenitor cells and lymphoid lineage specification during hematopoiesis (By similarity)