Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton)
1_MALVF 6_ QFGQP 11_ VRAQP 16_ LPGLC 21_ HGKLI 26_ RTNAC 31_ DVCNS 36_ TDLPE 41_ VEIIS 46_ LLEEQ 51_ LPHYK 56_ LRADT 61_ IYGYD 66_ HDDWL 71_ HTPLI 76_ SPDAN 81_ IDLTT 86_ EQIEE 91_ TLKYF 96_ LLCAE 101_ RVGQM 106_ TKTYN 111_ DIDAV 116_ TRLLE 121_ EKERD 126_ LELAA 131_ RIGQS 136_ LLKKN 141_ KTLTE 146_ RNELL 151_ EEQVE 156_ HIREE 161_ VSQLR 166_ HELSM 171_ KDELL 176_ QFYTS 181_ AAEES 186_ EPESV 191_ CSTPL 196_ KRNES 201_ SSSVQ 206_ NYFHL 211_ DSLQK 216_ KLKDL 221_ EEENV 226_ VLRSE 231_ ASQLK 236_ TETIT 241_ YEEKE 246_ QQLVN 251_ DCVKE 256_ LRDAN 261_ VQIAS 266_ ISEEL 271_ AKKTE 276_ DAARQ 281_ QEEIT 286_ HLLSQ 291_ IVDLQ 296_ KKAKA 301_ CAVEN 306_ EELVQ 311_ HLGAA 316_ KDAQR 321_ QLTAE 326_ LRELE 331_ DKYAE 336_ CMEML 341_ HEAQE 346_ ELKNL 351_ RNKTM 356_ PNTTS 361_ RRYHS 366_ LGLFP 371_ MDSLA 376_ AEIEG 381_ TMRKE 386_ LQLEE 391_ AESPD 396_ ITHQK 401_ RVFET 406_ VRNIN 411_ QVVKQ 416_ RSLTP 421_ SPMNI 426_ PGSNQ 431_ SSAMN 436_ SLLSS 441_ CVSTP 446_ RSSFY 451_ GSDIG 456_ NVVLD 461_ NKTNS 466_ IILET 471_ EAADL 476_ GNDER 481_ SKKPG 486_ TPGTP 491_ GSHDL 496_ ETALR 501_ RLSLR 506_ RENYL 511_ SERRF 516_ FEEEQ 521_ ERKLQ 526_ ELAEK 531_ GELRS 536_ GSLTP 541_ TESIM 546_ SLGTH 551_ SRFSE 556_ FTGFS 561_ GMSFS 566_ SRSYL 571_ PEKLQ 576_ IVKPL 581_ EGSAT 586_ LHHWQ 591_ QLAQP 596_ HLGGI 601_ LDPRP 606_ GVVTK 611_ GFRTL 616_ DVDLD 621_ EVYCL 626_ NDFEE 631_ DDTGD 636_ HISLP 641_ RLATS 646_ TPVQH 651_ PETSA 656_ HHPGK 661_ CMSQT 666_ NSTFT 671_ FTTCR 676_ ILHPS 681_ DELTR 686_ VTPSL 691_ NSAPT 696_ PACGS 701_ TSHLK 706_ STPVA 711_ TPCTP 716_ RRLSL 721_ AESFT 726_ NTRES 731_ TTTMS 736_ TSLGL 741_ VWLLK 746_ ERGIS 751_ AAVYD 756_ PQSWD 761_ RAGRG 766_ SLLHS 771_ YTPKM 776_ AVIPS 781_ TPPNS 786_ PMQTP 791_ TSSPP 796_ SFEFK 801_ CTSPP 806_ YDNFL 811_ ASKPA 816_ SSILR 821_ EVREK 826_ NVRSS 831_ ESQTD 836_ VSVSN 841_ LNLVD 846_ KVRRF 851_ GVAKV 856_ VNSGR 861_ AHVPT 866_ LTEEQ 871_ GPLLC 876_ GPPGP 881_ APALV 886_ PRGLV 891_ PEGLP 896_ LRCPT 901_ VTSAI 906_ GGLQL 911_ NSGIR 916_ RNRSF 921_ PTMVG 926_ SSMQM 931_ KAPVT 936_ LTSGI 941_ LMGAK 946_LSKQT
1: Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors (PubMed:18675823). Involved in mitochondrial motility. When O-glycosylated, abolishes mitochondrial motility. Crucial for recruiting OGT to the mitochondrial surface of neuronal processes (PubMed:24995978). TRAK1 and RHOT form an essential protein complex that links KIF5 to mitochondria for light chain-independent, anterograde transport of mitochondria (By similarity)