Major intrinsically disordered Notch2-binding receptor 1 (Membrane integral NOTCH2-associated receptor 1) (Ubiquitination and mTOR signaling protein)
1_METSQ 6_ ETSLF 11_ LVKIL 16_ EELDS 21_ KQNTV 26_ SYQDL 31_ CKSLC 36_ ARFDL 41_ SQLAK 46_ LRSVL 51_ FYTAC 56_ LDPNF 61_ PATLF 66_ KDKMK 71_ CTVNN 76_ QQSKK 81_ IMVAA 86_ DIVTI 91_ FNLIQ 96_ MNGGA 101_ AKEKL 106_ PTGRQ 111_ KVRKK 116_ EASFE 121_ SCRSD 126_ TEICN 131_ AAECE 136_ PLNCE 141_ LSERS 146_ FSRGY 151_ PIRQS 156_ SKCRK 161_ MDCKD 166_ CPQFV 171_ PASEP 176_ NFLLG 181_ VSKEV 186_ KNRAA 191_ SLDRL 196_ QALAP 201_ YSVTS 206_ PQPCE 211_ MQRTY 216_ FPMNI 221_ ENESI 226_ SDQDS 231_ LPINQ 236_ SIKET 241_ FISNE 246_ EPFVV 251_ QSCVQ 256_ KRNIF 261_ KEDFH 266_ NLMAV 271_ SPSLV 276_ GPISK 281_ AENEH 286_ REPQS 291_ RKEPH 296_ KPPFF 301_ NHSFE 306_ MPYNS 311_ QYLNP 316_ VYSPV 321_ PDKRR 326_ AKHES 331_ LDDLQ 336_ ASTYF 341_ GPTPV 346_ MGTQE 351_ ARRCL 356_ GKPNK 361_ QTPWP 366_ AKSWS 371_ LNTEE 376_ VPDFE 381_ RSFFN 386_ RNPSE 391_ EKLHY 396_ PNASS 401_ QTPNF 406_ PAPER 411_ RPTYL 416_ VPKDQ 421_ QPILP 426_ IAYAA 431_ KQNGL 436_ KSKEI 441_ SSPVD 446_ LEKHE 451_ PVKKF 456_ KDKSI 461_ NCTSG 466_ QLSSD 471_ TSSVG 476_ TQTEH 481_ VLEPK 486_ KCRDL 491_ CTSGQ 496_ GKYSD 501_ RHTMK 506_ HSDDD 511_ SEIVS 516_ DDISD 521_ IFRFL 526_ DDMSI 531_ SGSTG 536_ VIQSS 541_ CYNST 546_ GSLSQ 551_ LHKSD 556_ CDSSP 561_ EHNLT 566_ KIANG 571_ VPNSK 576_ GDKGN 581_ RPENT 586_ HHSEE 591_ ELKTS 596_ VCKLV 601_ LRIGE 606_ IERKL 611_ ESLSG 616_ VRDEI 621_ SQVLG 626_ KLNKL 631_ DQKMQ 636_ QPEKV 641_ SVQID 646_ LNSLT 651_ SEGPS 656_ DDSAS 661_ PRMFH 666_ AHSGS 671_ HGPKL 676_ ENNPD 681_ WCCSD 686_ ASGSN 691_ SESLR 696_ VKALK 701_ KSLFT 706_ RPSSR 711_ SLTEE 716_ NSATE 721_ SKIAS 726_ ISNSP 731_ RDWRT 736_ ITYTN 741_ RVGLN 746_ EEEIK 751_ DTGPG 756_ DNKDW 761_ HRKSK 766_ EADRQ 771_ YDIPP 776_ QHRLP 781_ KQPKD 786_ GFLVE 791_ QVFSP 796_ HPYPA 801_ SLKAH 806_ MKSNP 811_ LYTDM 816_ RLTEL 821_ AEVKR 826_ GQPSW 831_ TIEEY 836_ ARNAG 841_ DKGKL 846_ TALDL 851_ QTQES 856_ LNPNN 861_ LEYWM 866_ EDIYT 871_ PGYDS 876_ LLKRK 881_ EAEFR 886_ RAKVC 891_ KIAAL 896_ IAAAA 901_ CTVIL 906_ VIVVP 911_ICTMK
1: Intrinsically disordered protein which may negatively regulate mTOR signaling pathway by stabilizing the mTOR complex component DEPTOR (PubMed:30080879). Negatively regulates angiogenesis (PubMed:29329397). Negatively regulates cell growth (PubMed:29329397, PubMed:30080879). Negatively regulates neurite outgrowth in hippocampal neurons (By similarity)