Gene name: MGAT4B

Uniprot entry:

Q9UQ53

Protein names:

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)

Protein sequence:

1_MRLRN 6_ GTFLT 11_ LLLFC 16_ LCAFL 21_ SLSWY 26_ AALSG 31_ QKGDV 36_ VDVYQ 41_ REFLA 46_ LRDRL 51_ HAAEQ 56_ ESLKR 61_ SKELN 66_ LVLDE 71_ IKRAV 76_ SERQA 81_ LRDGD 86_ GNRTW 91_ GRLTE 96_ DPRLK 101_ PWNGS 106_ HRHVL 111_ HLPTV 116_ FHHLP 121_ HLLAK 126_ ESSLQ 131_ PAVRV 136_ GQGRT 141_ GVSVV 146_ MGIPS 151_ VRREV 156_ HSYLT 161_ DTLHS 166_ LISEL 171_ SPQEK 176_ EDSVI 181_ VVLIA 186_ ETDSQ 191_ YTSAV 196_ TENIK 201_ ALFPT 206_ EIHSG 211_ LLEVI 216_ SPSPH 221_ FYPDF 226_ SRLRE 231_ SFGDP 236_ KERVR 241_ WRTKQ 246_ NLDYC 251_ FLMMY 256_ AQSKG 261_ IYYVQ 266_ LEDDI 271_ VAKPN 276_ YLSTM 281_ KNFAL 286_ QQPSE 291_ DWMIL 296_ EFSQL 301_ GFIGK 306_ MFKSL 311_ DLSLI 316_ VEFIL 321_ MFYRD 326_ KPIDW 331_ LLDHI 336_ LWVKV 341_ CNPEK 346_ DAKHC 351_ DRQKA 356_ NLRIR 361_ FKPSL 366_ FQHVG 371_ THSSL 376_ AGKIQ 381_ KLKDK 386_ DFGKQ 391_ ALRKE 396_ HVNPP 401_ AEVST 406_ SLKTY 411_ QHFTL 416_ EKAYL 421_ REDFF 426_ WAFTP 431_ AAGDF 436_ IRFRF 441_ FQPLR 446_ LERFF 451_ FRSGN 456_ IEHPE 461_ DKLFN 466_ TSVEV 471_ LPFDN 476_ PQSDK 481_ EALQE 486_ GRTAT 491_ LRYPR 496_ SPDGY 501_ LQIGS 506_ FYKGV 511_ AEGEV 516_ DPAFG 521_ PLEAL 526_ RLSIQ 531_ TDSPV 536_ WVILS 541_EIFLK

Protein annotations

Protein functions:

1: Glycosyltransferase that catalyzes the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains (PubMed:10372966, PubMed:17006639). Prefers complex-type N-glycans over hybrid-types (PubMed:17006639). Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis (PubMed:17006639)