Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)
1_MSLSR 6_ SEEMH 11_ RLTEN 16_ VYKTI 21_ MEQFN 26_ PSLRN 31_ FIAMG 36_ KNYEK 41_ ALAGV 46_ TYAAK 51_ GYFDA 56_ LVKMG 61_ ELASE 66_ SQGSK 71_ ELGDV 76_ LFQMA 81_ EVHRQ 86_ IQNQL 91_ EEMLK 96_ SFHNE 101_ LLTQL 106_ EQKVE 111_ LDSRY 116_ LSAAL 121_ KKYQT 126_ EQRSK 131_ GDALD 136_ KCQAE 141_ LKKLR 146_ KKSQG 151_ SKNPQ 156_ KYSDK 161_ ELQYI 166_ DAISN 171_ KQGEL 176_ ENYVS 181_ DGYKT 186_ ALTEE 191_ RRRFC 196_ FLVEK 201_ QCAVA 206_ KNSAA 211_ YHSKG 216_ KELLA 221_ QKLPL 226_ WQQAC 231_ ADPSK 236_ IPERA 241_ VQLMQ 246_ QVASN 251_ GATLP 256_ SALSA 261_ SKSNL 266_ VISDP 271_ IPGAK 276_ PLPVP 281_ PELAP 286_ FVGRM 291_ SAQES 296_ TPIMN 301_ GVTGP 306_ DGEDY 311_ SPWAD 316_ RKAAQ 321_ PKSLS 326_ PPQSQ 331_ SKLSD 336_ SYSNT 341_ LPVRK 346_ SVTPK 351_ NSYAT 356_ TENKT 361_ LPRSS 366_ SMAAG 371_ LERNG 376_ RMRVK 381_ AIFSH 386_ AAGDN 391_ STLLS 396_ FKEGD 401_ LITLL 406_ VPEAR 411_ DGWHY 416_ GESEK 421_ TKMRG 426_ WFPFS 431_ YTRVL 436_ DSDGS 441_ DRLHM 446_ SLQQG 451_ KSSST 456_ GNLLD 461_ KDDLA 466_ IPPPD 471_ YGAAS 476_ RAFPA 481_ QTASG 486_ FKQRP 491_ YSVAV 496_ PAFSQ 501_ GLDDY 506_ GARSM 511_ SRNPF 516_ AHVQL 521_ KPTVT 526_ NDRCD 531_ LSAQG 536_ PEGRE 541_ HGDGS 546_ARTLA
1: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions