Protein phosphatase 1 regulatory subunit 3C (Protein phosphatase 1 regulatory subunit 5) (PP1 subunit R5) (Protein targeting to glycogen) (PTG)
1_MSCTR 6_ MIQVL 11_ DPRPL 16_ TSSVM 21_ PVDVA 26_ MRLCL 31_ AHSPP 36_ VKSFL 41_ GPYDE 46_ FQRRH 51_ FVNKL 56_ KPLKS 61_ CLNIK 66_ HKAKS 71_ QNDWK 76_ CSHNQ 81_ AKKRV 86_ VFADS 91_ KGLSL 96_ TAIHV 101_ FSDLP 106_ EEPAW 111_ DLQFD 116_ LLDLN 121_ DISSA 126_ LKHHE 131_ EKNLI 136_ LDFPQ 141_ PSTDY 146_ LSFRS 151_ HFQKN 156_ FVCLE 161_ NCSLQ 166_ ERTVT 171_ GTVKV 176_ KNVSF 181_ EKKVQ 186_ IRITF 191_ DSWKN 196_ YTDVD 201_ CVYMK 206_ NVYGG 211_ TDSDT 216_ FSFAI 221_ DLPPV 226_ IPTEQ 231_ KIEFC 236_ ISYHA 241_ NGQVF 246_ WDNND 251_ GQNYR 256_ IVHVQ 261_ WKPDG 266_ VQTQM 271_ APQDC 276_ AFHQT 281_ SPKTE 286_ LESTI 291_ FGSPR 296_ LASGL 301_ FPEWQ 306_ SWGRM 311_ENLAS
1: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types