C->U-editing enzyme APOBEC-2 (EC 3.5.4.36) (mRNA(cytosine(6666)) deaminase 2)
1_MAQKE 6_ EAAVA 11_ TEAAS 16_ QNGED 21_ LENLD 26_ DPEKL 31_ KELIE 36_ LPPFE 41_ IVTGE 46_ RLPAN 51_ FFKFQ 56_ FRNVE 61_ YSSGR 66_ NKTFL 71_ CYVVE 76_ AQGKG 81_ GQVQA 86_ SRGYL 91_ EDEHA 96_ AAHAE 101_ EAFFN 106_ TILPA 111_ FDPAL 116_ RYNVT 121_ WYVSS 126_ SPCAA 131_ CADRI 136_ IKTLS 141_ KTKNL 146_ RLLIL 151_ VGRLF 156_ MWEEP 161_ EIQAA 166_ LKKLK 171_ EAGCK 176_ LRIMK 181_ PQDFE 186_ YVWQN 191_ FVEQE 196_ EGESK 201_ AFQPW 206_ EDIQE 211_ NFLYY 216_EEKLA
1: Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation