E3 ubiquitin-protein ligase DTX4 (EC 2.3.2.27) (Protein deltex-4) (Deltex4) (RING finger protein 155) (RING-type E3 ubiquitin transferase DTX4)
1_MLLAS 6_ AVVVW 11_ EWLNE 16_ HGRWR 21_ PYSPA 26_ VSHHI 31_ EAVVR 36_ AGPRA 41_ GGSVV 46_ LGQVD 51_ SRLAP 56_ YIIDL 61_ QSMNQ 66_ FRQDT 71_ GTLRP 76_ VRRNY 81_ YDPSS 86_ APGKG 91_ VVWEW 96_ ENDNG 101_ SWTPY 106_ DMEVG 111_ ITIQH 116_ AYEKQ 121_ HPWID 126_ LTSIG 131_ FSYVI 136_ DFNTM 141_ GQINR 146_ QTQRQ 151_ RRVRR 156_ RLDLI 161_ YPMVT 166_ GTLPK 171_ AQSWP 176_ VSPGP 181_ ATSPP 186_ MSPCS 191_ CPQCV 196_ LVMSV 201_ KAAVV 206_ NGSTG 211_ PLQLP 216_ VTRKN 221_ MPPPG 226_ VVKLP 231_ PLPGS 236_ GAKPL 241_ DSTGT 246_ IRGPL 251_ KTAPS 256_ QVIRR 261_ QASSM 266_ PTGTT 271_ MGSPA 276_ SPPGP 281_ NSKTG 286_ RVALA 291_ TLNRT 296_ NLQRL 301_ AIAQS 306_ RVLIA 311_ SGVPT 316_ VPVKN 321_ LNGSS 326_ PVNPA 331_ LAGIT 336_ GILMS 341_ AAGLP 346_ VCLTR 351_ PPKLV 356_ LHPPP 361_ VSKSE 366_ IKSIP 371_ GVSNT 376_ SRKTT 381_ KKQAK 386_ KGKTP 391_ EEVLK 396_ KYLQK 401_ VRHPP 406_ DEDCT 411_ ICMER 416_ LTAPS 421_ GYKGP 426_ QPTVK 431_ PDLVG 436_ KLSRC 441_ GHVYH 446_ IYCLV 451_ AMYNN 456_ GNKDG 461_ SLQCP 466_ TCKTI 471_ YGVKT 476_ GTQPP 481_ GKMEY 486_ HLIPH 491_ SLPGH 496_ PDCKT 501_ IRIIY 506_ SIPPG 511_ IQGPE 516_ HPNPG 521_ KSFSA 526_ RGFPR 531_ HCYLP 536_ DSEKG 541_ RKVLK 546_ LLLVA 551_ WDRRL 556_ IFAIG 561_ TSSTT 566_ GESDT 571_ VIWNE 576_ VHHKT 581_ EFGSN 586_ LTGHG 591_ YPDAN 596_ YLDNV 601_ LAELA 606_ AQGIS 611_EDSTA
1: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4