Rabphilin-3A (Exophilin-1)
1_MTDTV 6_ FSNSS 11_ NRWMY 16_ PSDRP 21_ LQSND 26_ KEQLQ 31_ AGWSV 36_ HPGGQ 41_ PDRQR 46_ KQEEL 51_ TDEEK 56_ EIINR 61_ VIARA 66_ EKMEE 71_ MEQER 76_ IGRLV 81_ DRLEN 86_ MRKNV 91_ AGDGV 96_ NRCIL 101_ CGEQL 106_ GMLGS 111_ ACVVC 116_ EDCKK 121_ NVCTK 126_ CGVET 131_ NNRLH 136_ SVWLC 141_ KICIE 146_ QREVW 151_ KRSGA 156_ WFFKG 161_ FPKQV 166_ LPQPM 171_ PIKKT 176_ KPQQP 181_ VSEPA 186_ APEQP 191_ APEPK 196_ HPARA 201_ PARGD 206_ SEDRR 211_ GPGQK 216_ TGPDP 221_ ASAPG 226_ RGNYG 231_ PPVRR 236_ ASEAR 241_ MSSSS 246_ RDSES 251_ WDHSG 256_ GAGDS 261_ SRSPA 266_ GLRRA 271_ NSVQA 276_ SRPAP 281_ GSVQS 286_ PAPPQ 291_ PGQPG 296_ TPGGS 301_ RPGPG 306_ PAGRF 311_ PDQKP 316_ EVAPS 321_ DPGTT 326_ APPRE 331_ ERTGG 336_ VGGYP 341_ AVGAR 346_ EDRMS 351_ HPSGP 356_ YSQAS 361_ AAAPQ 366_ PAAAR 371_ QPPPP 376_ EEEEE 381_ EANSY 386_ DSDEA 391_ TTLGA 396_ LEFSL 401_ LYDQD 406_ NSSLQ 411_ CTIIK 416_ AKGLK 421_ PMDSN 426_ GLADP 431_ YVKLH 436_ LLPGA 441_ SKSNK 446_ LRTKT 451_ LRNTR 456_ NPIWN 461_ ETLVY 466_ HGITD 471_ EDMQR 476_ KTLRI 481_ SVCDE 486_ DKFGH 491_ NEFIG 496_ ETRFS 501_ LKKLK 506_ PNQRK 511_ NFNIC 516_ LERVI 521_ PMKRA 526_ GTTGS 531_ ARGMA 536_ LYEEE 541_ QVERV 546_ GDIEE 551_ RGKIL 556_ VSLMY 561_ STQQG 566_ GLIVG 571_ IIRCV 576_ HLAAM 581_ DANGY 586_ SDPFV 591_ KLWLK 596_ PDMGK 601_ KAKHK 606_ TQIKK 611_ KTLNP 616_ EFNEE 621_ FFYDI 626_ KHSDL 631_ AKKSL 636_ DISVW 641_ DYDIG 646_ KSNDY 651_ IGGCQ 656_ LGISA 661_ KGERL 666_ KHWYE 671_ CLKNK 676_ DKKIE 681_ RWHQL 686_QNENH
1: Plays an essential role in docking and fusion steps of regulated exocytosis (By similarity). At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP-dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release (By similarity). In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability. Also plays a role in the exocytosis of arginine vasopressin hormone (By similarity)