Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2)
1_MKKFN 6_ FRKVL 11_ DGLTA 16_ SSPGS 21_ GSSSG 26_ SNSGG 31_ GAGSG 36_ SVHPA 41_ GTAGV 46_ LREEI 51_ QETLT 56_ SEYFQ 61_ ICKTV 66_ RHGFP 71_ HQPTA 76_ LAFDP 81_ VQKIL 86_ AIGTR 91_ TGAIR 96_ ILGRP 101_ GVDCY 106_ CQHES 111_ GAAVL 116_ QLQFL 121_ INEGA 126_ LVSAS 131_ SDDTL 136_ HLWNL 141_ RQKRP 146_ AILHS 151_ LKFNR 156_ ERITY 161_ CHLPF 166_ QSKWL 171_ YVGTE 176_ RGNTH 181_ IVNIE 186_ SFILS 191_ GYVIM 196_ WNKAI 201_ ELSTK 206_ THPGP 211_ VVHLS 216_ DSPRD 221_ EGKLL 226_ IGYEN 231_ GTVVF 236_ WDLKS 241_ KRAEL 246_ RVYYD 251_ EAIHS 256_ IDWHH 261_ EGKQF 266_ MCSHS 271_ DGSLT 276_ LWNLK 281_ SPSRP 286_ FQTTI 291_ PHGKS 296_ QREGR 301_ KSESC 306_ KPILK 311_ VEYKT 316_ CKNSE 321_ PFIIF 326_ SGGLS 331_ YDKAC 336_ RRPSL 341_ TIMHG 346_ KAITV 351_ LEMDH 356_ PIVEF 361_ LTLCE 366_ TPYPN 371_ EFQEP 376_ YAVVV 381_ LLEKD 386_ LIVVD 391_ LTQSN 396_ FPIFE 401_ NPYPM 406_ DIHES 411_ PVTCT 416_ AYFAD 421_ CPPDL 426_ ILVLY 431_ SIGVK 436_ HKKQG 441_ YSNKE 446_ WPISG 451_ GAWNL 456_ GAQTY 461_ PEIII 466_ TGHAD 471_ GSIKF 476_ WDASA 481_ ITLQM 486_ LYKLK 491_ TSKVF 496_ EKQKV 501_ GEGKQ 506_ TCEIV 511_ EEDPF 516_ AIQMI 521_ YWCPE 526_ SRIFC 531_ VSGVS 536_ AYVII 541_ YKFSR 546_ HEITT 551_ EIVSL 556_ EVRLQ 561_ YDVED 566_ IITPE 571_ PETSP 576_ PFPDL 581_ SAQLP 586_ SSRSL 591_ SGSTN 596_ TVASE 601_ GVTKD 606_ SIPCL 611_ NVKTR 616_ PVRMP 621_ PGYQA 626_ ELVIQ 631_ LVWVD 636_ GEPPQ 641_ QITSL 646_ AVSSA 651_ YGIVA 656_ FGNCN 661_ GLAVV 666_ DFIQK 671_ TVLLS 676_ MGTID 681_ LYRSS 686_ DLYQR 691_ QPRSP 696_ RKNKQ 701_ FIADN 706_ FCMRG 711_ LSNFY 716_ PDLTK 721_ RIRTS 726_ YQSLT 731_ ELNDS 736_ PVPLE 741_ LERCK 746_ SPTSD 751_ HVNGH 756_ CTSPT 761_ SQSCS 766_ SGKRL 771_ SSADV 776_ SKVNR 781_ WGPGR 786_ PPFRK 791_ AQSAA 796_ CMEIS 801_ LPVTT 806_ EENRE 811_ NSYNR 816_ SRSSS 821_ ISSID 826_ KDSKE 831_ AITAL 836_ YFMDS 841_ FARKN 846_ DSTIS 851_ PCLFV 856_ GTSLG 861_ MVLII 866_ SLNLP 871_ LADEQ 876_ RFTEP 881_ VMVLP 886_ SGTFL 891_ SLKGA 896_ VLTFS 901_ CMDRM 906_ GGLMQ 911_ PPYEV 916_ WRDPN 921_ NIDEN 926_ EKSWR 931_ RKVVM 936_ NSSSA 941_ SQEIG 946_ DHQYT 951_ IICSE 956_ KQAKV 961_ FSLPS 966_ QTCLY 971_ VHNIT 976_ ETSFI 981_ LQANV 986_ VVMCS 991_ SACLA 996_ CFCAN 1001_ GHIMI 1006_ MSLPS 1011_ LRPML 1016_ DVNYL 1021_ PLTDM 1026_ RIART 1031_ FCFTN 1036_ EGQAL 1041_ YLVSP 1046_ TEIQR 1051_ LTYSQ 1056_ EMCDN 1061_ LQDML 1066_ GDLFT 1071_ PIETP 1076_ EAQNR 1081_ GFLKG 1086_ LFGGS 1091_ GQTFD 1096_ REELF 1101_ GEASA 1106_ GKASR 1111_ SLAQH 1116_ IPGPG 1121_ SIEGM 1126_ KGAAG 1131_ GVMGE 1136_ LTRAR 1141_ IALDE 1146_ RGQRL 1151_ GELEE 1156_ KTAGM 1161_ MTSAE 1166_ AFSKH 1171_ AHELM 1176_ LKYKD 1181_KKWYQ
1: Plays a role in vesicle trafficking and exocytosis inhibition. In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating STX1A and STX4, key t-SNARE proteins involved in the fusion of insulin granules to the plasma membrane. Also plays a role in neurotransmitter release by inhibiting basal acetylcholine release from axon terminals and by preventing synaptic fatigue upon repetitive stimulation (By similarity). Promotes as well axonal outgrowth (PubMed:25504045)