Gene name: COA3

Uniprot entry:

Q9Y2R0

Protein names:

Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (Coiled-coil domain-containing protein 56) (Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa)

Protein sequence:

1_MASSG 6_ AGDPL 11_ DSKRG 16_ EAPFA 21_ QRIDP 26_ TREKL 31_ TPEQL 36_ HSMRQ 41_ AELAQ 46_ WQKVL 51_ PRRRT 56_ RNIVT 61_ GLGIG 66_ ALVLA 71_ IYGYT 76_ FYSIS 81_ QERFL 86_ DELED 91_ EAKAA 96_ RARAL 101_ARASG

Protein annotations

Protein functions:

1: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly