Gene name: YBX2

Uniprot entry:

Q9Y2T7

Protein names:

Y-box-binding protein 2 (Contrin) (DNA-binding protein C) (Dbpc) (Germ cell-specific Y-box-binding protein) (MSY2 homolog)

Protein sequence:

1_MSEVE 6_ AAAGA 11_ TAVPA 16_ ATVPA 21_ TAAGV 26_ VAVVV 31_ PVPAG 36_ EPQKG 41_ GGAGG 46_ GGGAA 51_ SGPAA 56_ GTPSA 61_ PGSRT 66_ PGNPA 71_ TAVSG 76_ TPAPP 81_ ARSQA 86_ DKPVL 91_ AIQVL 96_ GTVKW 101_ FNVRN 106_ GYGFI 111_ NRNDT 116_ KEDVF 121_ VHQTA 126_ IKRNN 131_ PRKFL 136_ RSVGD 141_ GETVE 146_ FDVVE 151_ GEKGA 156_ EATNV 161_ TGPGG 166_ VPVKG 171_ SRYAP 176_ NRRKS 181_ RRFIP 186_ RPPSV 191_ APPPM 196_ VAEIP 201_ SAGTG 206_ PGSKG 211_ ERAED 216_ SGQRP 221_ RRWCP 226_ PPFFY 231_ RRRFV 236_ RGPRP 241_ PNQQQ 246_ PIEGT 251_ DRVEP 256_ KETAP 261_ LEGHQ 266_ QQGDE 271_ RVPPP 276_ RFRPR 281_ YRRPF 286_ RPRPR 291_ QQPTT 296_ EGGDG 301_ ETKPS 306_ QGPAD 311_ GSRPE 316_ PQRPR 321_ NRPYF 326_ QRRRQ 331_ QAPGP 336_ QQAPG 341_ PRQPA 346_ APETS 351_ APVNS 356_GDPTT

Protein annotations

Protein functions:

1: Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay (By similarity)