Tudor and KH domain-containing protein (Tudor domain-containing protein 2)
1_MSTER 6_ TSWTS 11_ LSTIQ 16_ KIALG 21_ LGIPA 26_ SATVA 31_ YILYR 36_ RYRES 41_ REERL 46_ TFVGE 51_ DDIEI 56_ EMRVP 61_ QEAVK 66_ LIIGR 71_ QGANI 76_ KQLRK 81_ QTGAR 86_ IDVDT 91_ EDVGD 96_ ERVLL 101_ ISGFP 106_ VQVCK 111_ AKAAI 116_ HQILT 121_ ENTPV 126_ SEQLS 131_ VPQRS 136_ VGRII 141_ GRGGE 146_ TIRSI 151_ CKASG 156_ AKITC 161_ DKESE 166_ GTLLL 171_ SRLIK 176_ ISGTQ 181_ KEVAA 186_ AKHLI 191_ LEKVS 196_ EDEEL 201_ RKRIA 206_ HSAET 211_ RVPRK 216_ QPISV 221_ RREDM 226_ TEPGG 231_ AGEPA 236_ LWKNT 241_ SSSME 246_ PTAPL 251_ VTPPP 256_ KGGGD 261_ MAVVV 266_ SKEGS 271_ WEKPS 276_ DDSFQ 281_ KSEAQ 286_ AIPEM 291_ PMFEI 296_ PSPDF 301_ SFHAD 306_ EYLEV 311_ YVSAS 316_ EHPNH 321_ FWIQI 326_ VGSRS 331_ LQLDK 336_ LVNEM 341_ TQHYE 346_ NSVPE 351_ DLTVH 356_ VGDIV 361_ AAPLP 366_ TNGSW 371_ YRARV 376_ LGTLE 381_ NGNLD 386_ LYFVD 391_ FGDNG 396_ DCPLK 401_ DLRAL 406_ RSDFL 411_ SLPFQ 416_ AIECS 421_ LARIA 426_ PSGDQ 431_ WEEEA 436_ LDEFD 441_ RLTHC 446_ ADWKP 451_ LVAKI 456_ SSYVQ 461_ TGIST 466_ WPKIY 471_ LYDTS 476_ NGKKL 481_ DIGLE 486_ LVHKG 491_ YAIEL 496_ PEDIE 501_ ENRAV 506_ PDMLK 511_ DMATE 516_ TDASL 521_ STLLT 526_ ETKKS 531_ SGEIT 536_ HTLSC 541_ LSLSE 546_ AASMS 551_ GDDNL 556_EDDYL
1: Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules