Gene name: UBE2D4

Uniprot entry:

Q9Y2X8

Protein names:

Ubiquitin-conjugating enzyme E2 D4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D4) (HBUCE1) (Ubiquitin carrier protein D4) (Ubiquitin-protein ligase D4)

Protein sequence:

1_MALKR 6_ IQKEL 11_ TDLQR 16_ DPPAQ 21_ CSAGP 26_ VGDDL 31_ FHWQA 36_ TIMGP 41_ NDSPY 46_ QGGVF 51_ FLTIH 56_ FPTDY 61_ PFKPP 66_ KVAFT 71_ TKIYH 76_ PNINS 81_ NGSIC 86_ LDILR 91_ SQWSP 96_ ALTVS 101_ KVLLS 106_ ICSLL 111_ CDPNP 116_ DDPLV 121_ PEIAH 126_ TYKAD 131_ REKYN 136_ RLARE 141_WTQKY

Protein annotations

Protein functions:

1: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11' and 'Lys-48'-linked polyubiquitination