Gene name: TMEM98

Uniprot entry:

Q9Y2Y6

Protein names:

Transmembrane protein 98 (Protein TADA1)

Protein sequence:

1_METVV 6_ IVAIG 11_ VLATI 16_ FLASF 21_ AALVL 26_ VCRQR 31_ YCRPR 36_ DLLQR 41_ YDSKP 46_ IVDLI 51_ GAMET 56_ QSEPS 61_ ELELD 66_ DVVIT 71_ NPHIE 76_ AILEN 81_ EDWIE 86_ DASGL 91_ MSHCI 96_ AILKI 101_ CHTLT 106_ EKLVA 111_ MTMGS 116_ GAKMK 121_ TSASV 126_ SDIIV 131_ VAKRI 136_ SPRVD 141_ DVVKS 146_ MYPPL 151_ DPKLL 156_ DARTT 161_ ALLLS 166_ VSHLV 171_ LVTRN 176_ ACHLT 181_ GGLDW 186_ IDQSL 191_ SAAEE 196_ HLEVL 201_ REAAL 206_ ASEPD 211_ KGLPG 216_ PEGFL 221_QEQSA

Protein annotations

Protein functions:

1: Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1)