Gene name: KLF13

Uniprot entry:

Q9Y2Y9

Protein names:

Krueppel-like factor 13 (Basic transcription element-binding protein 3) (BTE-binding protein 3) (Novel Sp1-like zinc finger transcription factor 1) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor BTEB3) (Transcription factor NSLP1)

Protein sequence:

1_MAAAA 6_ YVDHF 11_ AAECL 16_ VSMSS 21_ RAVVH 26_ GPREG 31_ PESRP 36_ EGAAV 41_ AATPT 46_ LPRVE 51_ ERRDG 56_ KDSAS 61_ LFVVA 66_ RILAD 71_ LNQQA 76_ PAPAP 81_ AERRE 86_ GAAAR 91_ KARTP 96_ CRLPP 101_ PAPEP 106_ TSPGA 111_ EGAAA 116_ APPSP 121_ AWSEP 126_ EPEAG 131_ LEPER 136_ EPGPA 141_ GSGEP 146_ GLRQR 151_ VRRGR 156_ SRADL 161_ ESPQR 166_ KHKCH 171_ YAGCE 176_ KVYGK 181_ SSHLK 186_ AHLRT 191_ HTGER 196_ PFACS 201_ WQDCN 206_ KKFAR 211_ SDELA 216_ RHYRT 221_ HTGEK 226_ KFSCP 231_ ICEKR 236_ FMRSD 241_ HLTKH 246_ ARRHA 251_ NFHPG 256_ MLQRR 261_ GGGSR 266_ TGSLS 271_ DYSRS 276_ DASSP 281_TISPA

Protein annotations

Protein functions:

1: Transcription factor that activates expression from GC-rich minimal promoter regions, including genes in the cells of the erythroid lineage (By similarity). Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1 (PubMed:11477107). Activates RANTES and CCL5 expression in T-cells (PubMed:17513757)