N-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase) (EC 3.5.1.25) (Amidohydrolase domain-containing protein 2)
1_MRGEQ 6_ GAAGA 11_ RVLQF 16_ TNCRI 21_ LRGGK 26_ LLRED 31_ LWVRG 36_ GRILD 41_ PEKLF 46_ FEERR 51_ VADER 56_ RDCGG 61_ RILAP 66_ GFIDV 71_ QINGG 76_ FGVDF 81_ SQATE 86_ DVGSG 91_ VALVA 96_ RRILS 101_ HGVTS 106_ FCPTL 111_ VTSPP 116_ EVYHK 121_ VVPQI 126_ PVKSG 131_ GPHGA 136_ GVLGL 141_ HLEGP 146_ FISRE 151_ KRGAH 156_ PEAHL 161_ RSFEA 166_ DAFQD 171_ LLATY 176_ GPLDN 181_ VRIVT 186_ LAPEL 191_ GRSHE 196_ VIRAL 201_ TARGI 206_ CVSLG 211_ HSVAD 216_ LRAAE 221_ DAVWS 226_ GATFI 231_ THLFN 236_ AMLPF 241_ HHRDP 246_ GIVGL 251_ LTSDR 256_ LPAGR 261_ CIFYG 266_ MIADG 271_ THTNP 276_ AALRI 281_ AHRAH 286_ PQGLV 291_ LVTDA 296_ IPALG 301_ LGNGR 306_ HTLGQ 311_ QEVEV 316_ DGLTA 321_ YVAGT 326_ KTLSG 331_ SIAPM 336_ DVCVR 341_ HFLQA 346_ TGCSM 351_ ESALE 356_ AASLH 361_ PAQLL 366_ GLEKS 371_ KGTLD 376_ FGADA 381_ DFVVL 386_ DDSLH 391_ VQATY 396_ ISGEL 401_VWQAD
1: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded