U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)
1_MLFYS 6_ FFKSL 11_ VGKDV 16_ VVELK 21_ NDLSI 26_ CGTLH 31_ SVDQY 36_ LNIKL 41_ TDISV 46_ TDPEK 51_ YPHML 56_ SVKNC 61_ FIRGS 66_ VVRYV 71_ QLPAD 76_ EVDTQ 81_ LLQDA 86_ARKEA
1: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320)