Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit SOH1) (hSOH1)
1_MAAAV 6_ AMETD 11_ DAGNR 16_ LRFQL 21_ ELEFV 26_ QCLAN 31_ PNYLN 36_ FLAQR 41_ GYFKD 46_ KAFVN 51_ YLKYL 56_ LYWKD 61_ PEYAK 66_ YLKYP 71_ QCLHM 76_ LELLQ 81_ YEHFR 86_ KELVN 91_ AQCAK 96_ FIDEQ 101_ QILHW 106_ QHYSR 111_ KRMRL 116_ QQALA 121_ EQQQQ 126_NNTSG
1: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors