Protein chibby homolog 1 (ARPP-binding protein) (Cytosolic leucine-rich protein) (PIGEA-14) (PKD2 interactor, Golgi and endoplasmic reticulum-associated 1)
1_MPFFG 6_ NTFSP 11_ KKTPP 16_ RKSAS 21_ LSNLH 26_ SLDRS 31_ TREVE 36_ LGLEY 41_ GSPTM 46_ NLAGQ 51_ SLKFE 56_ NGQWI 61_ AETGV 66_ SGGVD 71_ RREVQ 76_ RLRRR 81_ NQQLE 86_ EENNL 91_ LRLKV 96_ DILLD 101_ MLSES 106_ TAESH 111_ LMEKE 116_ LDELR 121_ISRKR
1: Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors (PubMed:12712206, PubMed:19435523). Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins (PubMed:15194699). Promotes adipocyte and cardiomyocyte differentiation (By similarity)