Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
1_MDKLP 6_ PSMRK 11_ RLYSL 16_ PQQVG 21_ AKAWI 26_ MDEEE 31_ DAEEE 36_ GAGGR 41_ QDPSR 46_ RSIRL 51_ RPLPS 56_ PSPSA 61_ AAGGT 66_ ESRSS 71_ ALGAA 76_ DSEGP 81_ ARGAG 86_ KSSTN 91_ GDCRR 96_ FRGSL 101_ ASLGS 106_ RGGGS 111_ GGTGS 116_ GSSHG 121_ HLHDS 126_ AEERR 131_ LIAEG 136_ DASPG 141_ EDRTP 146_ PGLAA 151_ EPERP 156_ GASAQ 161_ PAASP 166_ PPPQQ 171_ PPQPA 176_ SASCE 181_ QPSVD 186_ TAIKV 191_ EGGAA 196_ AGDQI 201_ LPEAE 206_ VRLGQ 211_ AGFMQ 216_ RQFGA 221_ MLQPG 226_ VNKFS 231_ LRMFG 236_ SQKAV 241_ EREQE 246_ RVKSA 251_ GFWII 256_ HPYSD 261_ FRFYW 266_ DLTML 271_ LLMVG 276_ NLIII 281_ PVGIT 286_ FFKDE 291_ NTTPW 296_ IVFNV 301_ VSDTF 306_ FLIDL 311_ VLNFR 316_ TGIVV 321_ EDNTE 326_ IILDP 331_ QRIKM 336_ KYLKS 341_ WFMVD 346_ FISSI 351_ PVDYI 356_ FLIVE 361_ TRIDS 366_ EVYKT 371_ ARALR 376_ IVRFT 381_ KILSL 386_ LRLLR 391_ LSRLI 396_ RYIHQ 401_ WEEIF 406_ HMTYD 411_ LASAV 416_ VRIVN 421_ LIGMM 426_ LLLCH 431_ WDGCL 436_ QFLVP 441_ MLQDF 446_ PDDCW 451_ VSINN 456_ MVNNS 461_ WGKQY 466_ SYALF 471_ KAMSH 476_ MLCIG 481_ YGRQA 486_ PVGMS 491_ DVWLT 496_ MLSMI 501_ VGATC 506_ YAMFI 511_ GHATA 516_ LIQSL 521_ DSSRR 526_ QYQEK 531_ YKQVE 536_ QYMSF 541_ HKLPP 546_ DTRQR 551_ IHDYY 556_ EHRYQ 561_ GKMFD 566_ EESIL 571_ GELSE 576_ PLREE 581_ IINFN 586_ CRKLV 591_ ASMPL 596_ FANAD 601_ PNFVT 606_ SMLTK 611_ LRFEV 616_ FQPGD 621_ YIIRE 626_ GTIGK 631_ KMYFI 636_ QHGVV 641_ SVLTK 646_ GNKET 651_ KLADG 656_ SYFGE 661_ ICLLT 666_ RGRRT 671_ ASVRA 676_ DTYCR 681_ LYSLS 686_ VDNFN 691_ EVLEE 696_ YPMMR 701_ RAFET 706_ VALDR 711_ LDRIG 716_ KKNSI 721_ LLHKV 726_ QHDLN 731_ SGVFN 736_ YQENE 741_ IIQQI 746_ VQHDR 751_ EMAHC 756_ AHRVQ 761_ AAASA 766_ TPTPT 771_ PVIWT 776_ PLIQA 781_ PLQAA 786_ AATTS 791_ VAIAL 796_ THHPR 801_ LPAAI 806_ FRPPP 811_ GSGLG 816_ NLGAG 821_ QTPRH 826_ LKRLQ 831_ SLIPS 836_ ALGSA 841_ SPASS 846_ PSQVD 851_ TPSSS 856_ SFHIQ 861_ QLAGF 866_ SAPAG 871_ LSPLL 876_ PSSSS 881_ SPPPG 886_ ACGSP 891_ SAPTP 896_ SAGVA 901_ ATTIA 906_ GFGHF 911_ HKALG 916_ GSLSS 921_ SDSPL 926_ LTPLQ 931_ PGARS 936_ PQAAQ 941_ PSPAP 946_ PGARG 951_ GLGLP 956_ EHFLP 961_ PPPSS 966_ RSPSS 971_ SPGQL 976_ GQPPG 981_ ELSLG 986_ LATGP 991_ LSTPE 996_ TPPRQ 1001_ PEPPS 1006_ LVAGA 1011_ SGGAS 1016_ PVGFT 1021_ PRGGL 1026_ SPPGH 1031_ SPGPP 1036_ RTFPS 1041_ APPRA 1046_ SGSHG 1051_ SLLLP 1056_ PASSP 1061_ PPPQV 1066_ PQRRG 1071_ TPPLT 1076_ PGRLT 1081_ QDLKL 1086_ ISASQ 1091_ PALPQ 1096_ DGAQT 1101_ LRRAS 1106_ PHSSG 1111_ ESMAA 1116_ FPLFP 1121_ RAGGG 1126_ SGGSG 1131_ SSGGL 1136_ GPPGR 1141_ PYGAI 1146_ PGQHV 1151_ TLPRK 1156_ TSSGS 1161_ LPPPL 1166_ SLFGA 1171_ RATSS 1176_ GGPPL 1181_ TAGPQ 1186_ REPGA 1191_ RPEPV 1196_RSKLP
1: Hyperpolarization-activated ion channel that are permeable to Na(+) and K(+) ions with very slow activation and inactivation (PubMed:10228147, PubMed:10430953, PubMed:20829353). Exhibits higher selectivity for K(+) over Na(+) ions (PubMed:10228147). Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat (Probable) (PubMed:10228147, PubMed:16407510, PubMed:19165230). Contributes to the native pacemaker currents in neurons (Ih) (Probable). May mediate responses to sour stimuli (By similarity)