TOG array regulator of axonemal microtubules protein 1 (Crescerin-1) (Protein FAM179B)
1_MAAAP 6_ SALLL 11_ LPPFP 16_ VLSTY 21_ RLQSR 26_ SRPSA 31_ PETDD 36_ SRVGG 41_ IMRGE 46_ KNYYF 51_ RGAAG 56_ DHGSC 61_ PTTTS 66_ PLASA 71_ LLMPS 76_ EAVSS 81_ SWSES 86_ GGGLS 91_ GGDEE 96_ DTRLL 101_ QLLRT 106_ ARDPS 111_ EAFQA 116_ LQAAL 121_ PRRGG 126_ RLGFP 131_ RRKEA 136_ LYRAL 141_ GRVLV 146_ EGGSD 151_ EKRLC 156_ LQLLS 161_ DVLRG 166_ QGEAG 171_ QLEEA 176_ FSLAL 181_ LPQLV 186_ VSLRE 191_ ENPAL 196_ RKDAL 201_ QILHI 206_ CLKRS 211_ PGEVL 216_ RTLIQ 221_ QGLES 226_ TDARL 231_ RASTA 236_ LLLPI 241_ LLTTE 246_ DLLLG 251_ LDLTE 256_ VIISL 261_ ARKLG 266_ DQETE 271_ EESET 276_ AFSAL 281_ QQIGE 286_ RLGQD 291_ RFQSY 296_ ISRLP 301_ SALRR 306_ HYNRR 311_ LESQF 316_ GSQVP 321_ YYLEL 326_ EASGF 331_ PEDPL 336_ PCAVT 341_ LSNSN 346_ LKFGI 351_ IPQEL 356_ HSRLL 361_ DQEDY 366_ KNRTQ 371_ AVEEL 376_ KQVLG 381_ KFNPS 386_ STPHS 391_ SLVGF 396_ ISLLY 401_ NLLDD 406_ SNFKV 411_ VHGTL 416_ EVLHL 421_ LVIRL 426_ GEQVQ 431_ QFLGP 436_ VIAAS 441_ VKVLA 446_ DNKLV 451_ IKQEY 456_ MKIFL 461_ KLMKE 466_ VGPQQ 471_ VLCLL 476_ LEHLK 481_ HKHSR 486_ VREEV 491_ VNICI 496_ CSLLT 501_ YPSED 506_ FDLPK 511_ LSFDL 516_ APALV 521_ DSKRR 526_ VRQAA 531_ LEAFA 536_ VLASS 541_ MGSGK 546_ TSILF 551_ KAVDT 556_ VELQD 561_ NGDGV 566_ MNAVQ 571_ ARLAR 576_ KTLPR 581_ LTEQG 586_ FVEYA 591_ VLMPS 596_ SAGGR 601_ SNHLA 606_ HGADT 611_ DWLLA 616_ GNRTQ 621_ SAHCH 626_ CGDHV 631_ RDSMH 636_ IYGSY 641_ SPTIC 646_ TRRVL 651_ SAGKG 656_ KNKLP 661_ WENEQ 666_ PGIMG 671_ ENQTS 676_ TSKDI 681_ EQFST 686_ YDFIP 691_ SAKLK 696_ LSQGM 701_ PVNDD 706_ LCFSR 711_ KRVSR 716_ NLFQN 721_ SRDFN 726_ PDCLP 731_ LCAAG 736_ TTGTH 741_ QTNLS 746_ GKCAQ 751_ LGFSQ 756_ ICGKT 761_ GSVGS 766_ DLQFL 771_ GTTSS 776_ HQEKV 781_ YASLN 786_ FGSKT 791_ QQTFG 796_ SQTEC 801_ TSSNG 806_ QNPSP 811_ GAYIL 816_ PSYPV 821_ SSPRT 826_ SPKHT 831_ SPLII 836_ SPKKS 841_ QDNSV 846_ NFSNS 851_ WPLKS 856_ FEGLS 861_ KPSPQ 866_ KKLVS 871_ QKSSD 876_ PTGRN 881_ HGENS 886_ QEKPP 891_ VQLTP 896_ ALVRS 901_ PSSRR 906_ GLNGT 911_ KPVPP 916_ IPRGI 921_ SLLPD 926_ KADLS 931_ TVGHK 936_ KKEPD 941_ DIWKC 946_ EKDSL 951_ PIDLS 956_ ELNFK 961_ DKDLD 966_ QEEMH 971_ SSLRS 976_ LRNSA 981_ AKKRA 986_ KLSGS 991_ TSDLE 996_ SPDSA 1001_ MKLDL 1006_ TMDSP 1011_ SLSSS 1016_ PNINS 1021_ YSESG 1026_ VYSQE 1031_ SLTSS 1036_ LSTTP 1041_ QGKRI 1046_ MSDIF 1051_ PTFGS 1056_ KPCPT 1061_ RLSSA 1066_ KKKIS 1071_ HIAEQ 1076_ SPSAG 1081_ SSSNP 1086_ QQISS 1091_ FDFTT 1096_ TKALS 1101_ EDSVV 1106_ VVGKG 1111_ VFGSL 1116_ SSAPA 1121_ TCSQS 1126_ VISSV 1131_ ENGDT 1136_ FSIKQ 1141_ SIEPP 1146_ SGIYG 1151_ RSVQQ 1156_ NISSY 1161_ LDVEN 1166_ EKDAK 1171_ VSISK 1176_ STYNK 1181_ MRQKR 1186_ KEEKE 1191_ LFHNK 1196_ DCEKK 1201_ EKNSW 1206_ ERMRH 1211_ TGTEK 1216_ MASES 1221_ ETPTG 1226_ AISQY 1231_ KERMP 1236_ SVTHS 1241_ PEIMD 1246_ LSELR 1251_ PFSKP 1256_ EIALT 1261_ EALRL 1266_ LADED 1271_ WEKKI 1276_ EGLNF 1281_ IRCLA 1286_ AFHSE 1291_ ILNTK 1296_ LHETN 1301_ FAVVQ 1306_ EVKNL 1311_ RSGVS 1316_ RAAVV 1321_ CLSDL 1326_ FTYLK 1331_ KSMDQ 1336_ ELDTT 1341_ VKVLL 1346_ HKAGE 1351_ SNTFI 1356_ REDVD 1361_ KALRA 1366_ MVNNV 1371_ TPARA 1376_ VVSLI 1381_ NGGQR 1386_ YYGRK 1391_ MLFFM 1396_ MCHPN 1401_ FEKML 1406_ EKYVP 1411_ SKDLP 1416_ YIKDS 1421_ VRNLQ 1426_ QKGLG 1431_ EIPLD 1436_ TPSAK 1441_ GRRSH 1446_ TGSVG 1451_ NTRSS 1456_ SVSRD 1461_ AFNSA 1466_ ERAVT 1471_ EVREV 1476_ TRKSV 1481_ PRNSL 1486_ ESAEY 1491_ LKLIT 1496_ GLLNA 1501_ KDFRD 1506_ RINGI 1511_ KQLLS 1516_ DTENN 1521_ QDLVV 1526_ GNIVK 1531_ IFDAF 1536_ KSRLH 1541_ DSNSK 1546_ VNLVA 1551_ LETMH 1556_ KMIPL 1561_ LRDHL 1566_ SPIIN 1571_ MLIPA 1576_ IVDNN 1581_ LNSKN 1586_ PGIYA 1591_ AATNV 1596_ VQALS 1601_ QHVDN 1606_ YLLLQ 1611_ PFCTK 1616_ AQFLN 1621_ GKAKQ 1626_ DMTEK 1631_ LADIV 1636_ TELYQ 1641_ RKPHA 1646_ TEQKV 1651_ LVVLW 1656_ HLLGN 1661_ MTNSG 1666_ SLPGA 1671_ GGNIR 1676_ TATAK 1681_ LSKAL 1686_ FAQMG 1691_ QNLLN 1696_ QAASQ 1701_ PPHIK 1706_ KSLEE 1711_LLDMT
1: Involved in ciliogenesis (PubMed:32453716). It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length (PubMed:32453716). Interacts with microtubules and promotes microtubule polymerization via its HEAT repeat domains, especially those in TOG region 2 and 4 (By similarity)