Sperm flagellar protein 1
1_MASSV 6_ DEEAL 11_ HQLYL 16_ WVDNI 21_ PLSRP 26_ KRNLS 31_ RDFSD 36_ GVLVA 41_ EVIKF 46_ YFPKM 51_ VEMHN 56_ YVPAN 61_ SLQQK 66_ LSNWG 71_ HLNRK 76_ VLKRL 81_ NFSVP 86_ DDVMR 91_ KIAQC 96_ APGVV 101_ ELVLI 106_ PLRQR 111_ LEERQ 116_ RRRKQ 121_ GAGSL 126_ QELAP 131_ QDGSG 136_ YMDVG 141_ VSQKA 146_ RGEGV 151_ PDPQG 156_ GGQLS 161_ WDRPP 166_ APRPP 171_ AYNRA 176_ LQGDP 181_ SFVLQ 186_ IAEKE 191_ QELLA 196_ SQETV 201_ QVLQM 206_ KVRRL 211_ EHLLQ 216_ LKNVR 221_ IEDLS 226_ RRLQQ 231_AERKQ
1: Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation. Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (By similarity). Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock (By similarity). Essential for ciliary central apparatus formation which requires both its microtubule-binding and bundling activities and for ciliary localization of HYDIN and SPAG6 in ependymal cilia (By similarity). Binds actin in intestinal epithelial cells (IECs), essential for IECs survival and contributes to formation of filopodia and lamellipodia in migrating IECs (PubMed:31473225). Regulates planar cell polarity signaling pathway and asymmetric microtubule accumulation in ciliated epithelia (By similarity)