U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP)
1_MLPLS 6_ LLKTA 11_ QNHPM 16_ LVELK 21_ NGETY 26_ NGHLV 31_ SCDNW 36_ MNINL 41_ REVIC 46_ TSRDG 51_ DKFWR 56_ MPECY 61_ IRGST 66_ IKYLR 71_ IPDEI 76_ IDMVK 81_ EEVVA 86_ KGRGR 91_ GGLQQ 96_ QKQQK 101_ GRGMG 106_ GAGRG 111_ VFGGR 116_ GRGGI 121_ PGTGR 126_ GQPEK 131_KPGRQ
1: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320)