NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18)
1_MAQKK 6_ YLQAK 11_ LTQFL 16_ REDRI 21_ QLWKP 26_ PYTDE 31_ NKKVG 36_ LALKD 41_ LAKQY 46_ SDRLE 51_ CCENE 56_ VEKVI 61_ EEIRC 66_ KAIER 71_ GTGND 76_ NYRTT 81_ GIATI 86_ EVFLP 91_ PRLKK 96_ DRKNL 101_ LETRL 106_ HITGR 111_ ELRSK 116_ IAETF 121_ GLQEN 126_ YIKIV 131_ INKKQ 136_ LQLGK 141_ TLEEQ 146_ GVAHN 151_ VKAMV 156_ LELKQ 161_ SEEDA 166_ RKNFQ 171_ LEEEE 176_ QNEAK 181_ LKEKQ 186_ IQRTK 191_ RGLEI 196_ LAKRA 201_ AETVV 206_ DPEMT 211_ PYLDI 216_ ANQTG 221_ RSIRI 226_ PPSER 231_ KALML 236_ AMGYH 241_ EKGRA 246_ FLKRK 251_ EYGIA 256_ LPCLL 261_ DADKY 266_ FCECC 271_ RELLD 276_ TVDNY 281_ AVLQL 286_ DIVWC 291_ YFRLE 296_ QLECL 301_ DDAEK 306_ KLNLA 311_ QKCFK 316_ NCYGE 321_ NHQRL 326_ VHIKG 331_ NCGKE 336_ KVLFL 341_ RLYLL 346_ QGIRN 351_ YHSGN 356_ DVEAY 361_ EYLNK 366_ ARQLF 371_ KELYI 376_ DPSKV 381_ DNLLQ 386_ LGFTA 391_ QEARL 396_ GLRAC 401_ DGNVD 406_ HAATH 411_ ITNRR 416_ EELAQ 421_ IRKEE 426_ KEKKR 431_ RRLEN 436_ IRFLK 441_ GMGYS 446_ THAAQ 451_ QVLHA 456_ ASGNL 461_ DEALK 466_ ILLSN 471_ PQMWW 476_ LNDSN 481_ PETDN 486_ RQESP 491_ SQENI 496_ DRLVY 501_ MGFDA 506_ LVAEA 511_ ALRVF 516_ RGNVQ 521_ LAAQT 526_ LAHNG 531_ GSLPP 536_ ELPLS 541_ PEDSL 546_ SPPAT 551_ SPSDS 556_ AGTSS 561_ ASTDE 566_ DMETE 571_ AVNEI 576_ LEDIP 581_ EHEED 586_ YLDST 591_ LEDEE 596_ IIIAE 601_ YLSYV 606_ENRKS
1: Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2