Nucleoside diphosphate kinase 7 (NDK 7) (NDP kinase 7) (EC 2.7.4.6) (nm23-H7)
1_MNHSE 6_ RFVFI 11_ AEWYD 16_ PNASL 21_ LRRYE 26_ LLFYP 31_ GDGSV 36_ EMHDV 41_ KNHRT 46_ FLKRT 51_ KYDNL 56_ HLEDL 61_ FIGNK 66_ VNVFS 71_ RQLVL 76_ IDYGD 81_ QYTAR 86_ QLGSR 91_ KEKTL 96_ ALIKP 101_ DAISK 106_ AGEII 111_ EIINK 116_ AGFTI 121_ TKLKM 126_ MMLSR 131_ KEALD 136_ FHVDH 141_ QSRPF 146_ FNELI 151_ QFITT 156_ GPIIA 161_ MEILR 166_ DDAIC 171_ EWKRL 176_ LGPAN 181_ SGVAR 186_ TDASE 191_ SIRAL 196_ FGTDG 201_ IRNAA 206_ HGPDS 211_ FASAA 216_ REMEL 221_ FFPSS 226_ GGCGP 231_ ANTAK 236_ FTNCT 241_ CCIVK 246_ PHAVS 251_ EGLLG 256_ KILMA 261_ IRDAG 266_ FEISA 271_ MQMFN 276_ MDRVN 281_ VEEFY 286_ EVYKG 291_ VVTEY 296_ HDMVT 301_ EMYSG 306_ PCVAM 311_ EIQQN 316_ NATKT 321_ FREFC 326_ GPADP 331_ EIARH 336_ LRPGT 341_ LRAIF 346_ GKTKI 351_ QNAVH 356_ CTDLP 361_ EDGLL 366_ EVQYF 371_FKILD
1: Possesses an intrinsic kinase activity (PubMed:24807905). Displays 3'-5' exonuclease activity with a preference for single-stranded DNA (PubMed:16313181). Does not seem to have nucleoside diphosphate kinase activity (PubMed:16313181, PubMed:24807905). Functional component of the gamma-tubulin ring complex, implicated in the regulation of the microtubule-nucleating activity of the gamma-tubulin ring complex in centrosomes, in a kinase activity-dependent manner (PubMed:24807905). Part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189)