U3 small nucleolar RNA-associated protein 18 homolog (WD repeat-containing protein 50)
1_MPPER 6_ RRRMK 11_ LDRRT 16_ GAKPK 21_ RKPGM 26_ RPDWK 31_ AGAGP 36_ GGPPQ 41_ KPAPS 46_ SQRKP 51_ PARPS 56_ AAAAA 61_ IAVAA 66_ AEEER 71_ RLRQR 76_ NRLRL 81_ EEDKP 86_ AVERC 91_ LEELV 96_ FGDVE 101_ NDEDA 106_ LLRRL 111_ RGPRV 116_ QEHED 121_ SGDSE 126_ VENEA 131_ KGNFP 136_ PQKKP 141_ VWVDE 146_ EDEDE 151_ EMVDM 156_ MNNRF 161_ RKDMM 166_ KNASE 171_ SKLSK 176_ DNLKK 181_ RLKEE 186_ FQHAM 191_ GGVPA 196_ WAETT 201_ KRKTS 206_ SDDES 211_ EEDED 216_ DLLQR 221_ TGNFI 226_ STSTS 231_ LPRGI 236_ LKMKN 241_ CQHAN 246_ AERPT 251_ VARIS 256_ SVQFH 261_ PGAQI 266_ VMVAG 271_ LDNAV 276_ SLFQV 281_ DGKTN 286_ PKIQS 291_ IYLER 296_ FPIFK 301_ ACFSA 306_ NGEEV 311_ LATST 316_ HSKVL 321_ YVYDM 326_ LAGKL 331_ IPVHQ 336_ VRGLK 341_ EKIVR 346_ SFEVS 351_ PDGSF 356_ LLING 361_ IAGYL 366_ HLLAM 371_ KTKEL 376_ IGSMK 381_ INGRV 386_ AASTF 391_ SSDSK 396_ KVYAS 401_ SGDGE 406_ VYVWD 411_ VNSRK 416_ CLNRF 421_ VDEGS 426_ LYGLS 431_ IATSR 436_ NGQYV 441_ ACGSN 446_ CGVVN 451_ IYNQD 456_ SCLQE 461_ TNPKP 466_ IKAIM 471_ NLVTG 476_ VTSLT 481_ FNPTT 486_ EILAI 491_ ASEKM 496_ KEAVR 501_ LVHLP 506_ SCTVF 511_ SNFPV 516_ IKNKN 521_ ISHVH 526_ TMDFS 531_ PRSGY 536_ FALGN 541_ EKGKA 546_ LMYRL 551_HHYSD
1: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA