V-type proton ATPase subunit D (V-ATPase subunit D) (V-ATPase 28 kDa accessory protein) (Vacuolar proton pump subunit D)
1_MSGKD 6_ RIEIF 11_ PSRMA 16_ QTIMK 21_ ARLKG 26_ AQTGR 31_ NLLKK 36_ KSDAL 41_ TLRFR 46_ QILKK 51_ IIETK 56_ MLMGE 61_ VMREA 66_ AFSLA 71_ EAKFT 76_ AGDFS 81_ TTVIQ 86_ NVNKA 91_ QVKIR 96_ AKKDN 101_ VAGVT 106_ LPVFE 111_ HYHEG 116_ TDSYE 121_ LTGLA 126_ RGGEQ 131_ LAKLK 136_ RNYAK 141_ AVELL 146_ VELAS 151_ LQTSF 156_ VTLDE 161_ AIKIT 166_ NRRVN 171_ AIEHV 176_ IIPRI 181_ ERTLA 186_ YIITE 191_ LDERE 196_ REEFY 201_ RLKKI 206_ QEKKK 211_ ILKEK 216_ SEKDL 221_ EQRRA 226_ AGEVL 231_ EPANL 236_ LAEEK 241_DEDLL
1: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (PubMed:21844891)