Ectonucleoside triphosphate diphosphohydrolase 2 (NTPDase 2) (EC 3.6.1.-) (CD39 antigen-like 1) (Ecto-ATP diphosphohydrolase 2) (Ecto-ATPDase 2) (Ecto-ATPase 2)
1_MAGKV 6_ RSLLP 11_ PLLLA 16_ AAGLA 21_ GLLLL 26_ CVPTR 31_ DVREP 36_ PALKY 41_ GIVLD 46_ AGSSH 51_ TSMFI 56_ YKWPA 61_ DKEND 66_ TGIVG 71_ QHSSC 76_ DVPGG 81_ GISSY 86_ ADNPS 91_ GASQS 96_ LVGCL 101_ EQALQ 106_ DVPKE 111_ RHAGT 116_ PLYLG 121_ ATAGM 126_ RLLNL 131_ TNPEA 136_ STSVL 141_ MAVTH 146_ TLTQY 151_ PFDFR 156_ GARIL 161_ SGQEE 166_ GVFGW 171_ VTANY 176_ LLENF 181_ IKYGW 186_ VGRWF 191_ RPRKG 196_ TLGAM 201_ DLGGA 206_ STQIT 211_ FETTS 216_ PAEDR 221_ ASEVQ 226_ LHLYG 231_ QHYRV 236_ YTHSF 241_ LCYGR 246_ DQVLQ 251_ RLLAS 256_ ALQTH 261_ GFHPC 266_ WPRGF 271_ STQVL 276_ LGDVY 281_ QSPCT 286_ MAQRP 291_ QNFNS 296_ SARVS 301_ LSGSS 306_ DPHLC 311_ RDLVS 316_ GLFSF 321_ SSCPF 326_ SRCSF 331_ NGVFQ 336_ PPVAG 341_ NFVAF 346_ SAFFY 351_ TVDFL 356_ RTSMG 361_ LPVAT 366_ LQQLE 371_ AAAVN 376_ VCNQT 381_ WAQLQ 386_ ARVPG 391_ QRARL 396_ ADYCA 401_ GAMFV 406_ QQLLS 411_ RGYGF 416_ DERAF 421_ GGVIF 426_ QKKAA 431_ DTAVG 436_ WALGY 441_ MLNLT 446_ NLIPA 451_ DPPGL 456_ RKGTD 461_ FSSWV 466_ VLLLL 471_ FASAL 476_ LAALV 481_ LLLRQ 486_VHSAK
1: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP