Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1)
1_MTSPS 6_ SSPVF 11_ RLETL 16_ DGGQE 21_ DGSEA 26_ DRGKL 31_ DFGSG 36_ LPPME 41_ SQFQG 46_ EDRKF 51_ APQIR 56_ VNLNY 61_ RKGTG 66_ ASQPD 71_ PNRFD 76_ RDRLF 81_ NAVSR 86_ GVPED 91_ LAGLP 96_ EYLSK 101_ TSKYL 106_ TDSEY 111_ TEGST 116_ GKTCL 121_ MKAVL 126_ NLKDG 131_ VNACI 136_ LPLLQ 141_ IDRDS 146_ GNPQP 151_ LVNAQ 156_ CTDDY 161_ YRGHS 166_ ALHIA 171_ IEKRS 176_ LQCVK 181_ LLVEN 186_ GANVH 191_ ARACG 196_ RFFQK 201_ GQGTC 206_ FYFGE 211_ LPLSL 216_ AACTK 221_ QWDVV 226_ SYLLE 231_ NPHQP 236_ ASLQA 241_ TDSQG 246_ NTVLH 251_ ALVMI 256_ SDNSA 261_ ENIAL 266_ VTSMY 271_ DGLLQ 276_ AGARL 281_ CPTVQ 286_ LEDIR 291_ NLQDL 296_ TPLKL 301_ AAKEG 306_ KIEIF 311_ RHILQ 316_ REFSG 321_ LSHLS 326_ RKFTE 331_ WCYGP 336_ VRVSL 341_ YDLAS 346_ VDSCE 351_ ENSVL 356_ EIIAF 361_ HCKSP 366_ HRHRM 371_ VVLEP 376_ LNKLL 381_ QAKWD 386_ LLIPK 391_ FFLNF 396_ LCNLI 401_ YMFIF 406_ TAVAY 411_ HQPTL 416_ KKQAA 421_ PHLKA 426_ EVGNS 431_ MLLTG 436_ HILIL 441_ LGGIY 446_ LLVGQ 451_ LWYFW 456_ RRHVF 461_ IWISF 466_ IDSYF 471_ EILFL 476_ FQALL 481_ TVVSQ 486_ VLCFL 491_ AIEWY 496_ LPLLV 501_ SALVL 506_ GWLNL 511_ LYYTR 516_ GFQHT 521_ GIYSV 526_ MIQKV 531_ ILRDL 536_ LRFLL 541_ IYLVF 546_ LFGFA 551_ VALVS 556_ LSQEA 561_ WRPEA 566_ PTGPN 571_ ATESV 576_ QPMEG 581_ QEDEG 586_ NGAQY 591_ RGILE 596_ ASLEL 601_ FKFTI 606_ GMGEL 611_ AFQEQ 616_ LHFRG 621_ MVLLL 626_ LLAYV 631_ LLTYI 636_ LLLNM 641_ LIALM 646_ SETVN 651_ SVATD 656_ SWSIW 661_ KLQKA 666_ ISVLE 671_ MENGY 676_ WWCRK 681_ KQRAG 686_ VMLTV 691_ GTKPD 696_ GSPDE 701_ RWCFR 706_ VEEVN 711_ WASWE 716_ QTLPT 721_ LCEDP 726_ SGAGV 731_ PRTLE 736_ NPVLA 741_ SPPKE 746_ DEDGA 751_ SEENY 756_VPVQL
1: Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF1, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH