Sorting nexin-10
1_MFPEQ 6_ QKEEF 11_ VSVWV 16_ RDPRI 21_ QKEDF 26_ WHSYI 31_ DYEIC 36_ IHTNS 41_ MCFTM 46_ KTSCV 51_ RRRYR 56_ EFVWL 61_ RQRLQ 66_ SNALL 71_ VQLPE 76_ LPSKN 81_ LFFNM 86_ NNRQH 91_ VDQRR 96_ QGLED 101_ FLRKV 106_ LQNAL 111_ LLSDS 116_ SLHLF 121_ LQSHL 126_ NSEDI 131_ EACVS 136_ GQTKY 141_ SVEEA 146_ IHKFA 151_ LMNRR 156_ FPEED 161_ EEGKK 166_ ENDID 171_ YDSES 176_ SSSGL 181_ GHSSD 186_ DSSSH 191_ GCKVN 196_TAPQE
1: Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. Plays a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. Required for the localization to the cilium of V-ATPase subunit ATP6V1D and ATP6V0D1, and RAB8A. Involved in osteoclast differentiation and therefore bone resorption