Gene name: NR2E3

Uniprot entry:

Q9Y5X4

Protein names:

Photoreceptor-specific nuclear receptor (Nuclear receptor subfamily 2 group E member 3) (Retina-specific nuclear receptor)

Protein sequence:

1_METRP 6_ TALMS 11_ STVAA 16_ AAPAA 21_ GAASR 26_ KESPG 31_ RWGLG 36_ EDPTG 41_ VSPSL 46_ QCRVC 51_ GDSSS 56_ GKHYG 61_ IYACN 66_ GCSGF 71_ FKRSV 76_ RRRLI 81_ YRCQV 86_ GAGMC 91_ PVDKA 96_ HRNQC 101_ QACRL 106_ KKCLQ 111_ AGMNQ 116_ DAVQN 121_ ERQPR 126_ STAQV 131_ HLDSM 136_ ESNTE 141_ SRPES 146_ LVAPP 151_ APAGR 156_ SPRGP 161_ TPMSA 166_ ARALG 171_ HHFMA 176_ SLITA 181_ ETCAK 186_ LEPED 191_ ADENI 196_ DVTSN 201_ DPEFP 206_ SSPYS 211_ SSSPC 216_ GLDSI 221_ HETSA 226_ RLLFM 231_ AVKWA 236_ KNLPV 241_ FSSLP 246_ FRDQV 251_ ILLEE 256_ AWSEL 261_ FLLGA 266_ IQWSL 271_ PLDSC 276_ PLLAP 281_ PEASA 286_ AGGAQ 291_ GRLTL 296_ ASMET 301_ RVLQE 306_ TISRF 311_ RALAV 316_ DPTEF 321_ ACMKA 326_ LVLFK 331_ PETRG 336_ LKDPE 341_ HVEAL 346_ QDQSQ 351_ VMLSQ 356_ HSKAH 361_ HPSQP 366_ VRFGK 371_ LLLLL 376_ PSLRF 381_ ITAER 386_ IELLF 391_ FRKTI 396_ GNTPM 401_EKLLC

Protein annotations

Protein functions:

1: Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression