Gene name: ACTL7A

Uniprot entry:

Q9Y615

Protein names:

Actin-like protein 7A (Actin-like-7-alpha)

Protein sequence:

1_MWAPP 6_ AAIMG 11_ DGPTK 16_ KVGNQ 21_ APLQT 26_ QALQT 31_ ASLRD 36_ GPAKR 41_ AVWVR 46_ HTSSE 51_ PQEPT 56_ ESKAA 61_ KERPK 66_ QEVTK 71_ AVVVD 76_ LGTGY 81_ CKCGF 86_ AGLPR 91_ PTHKI 96_ STTVG 101_ KPYME 106_ TAKTG 111_ DNRKE 116_ TFVGQ 121_ ELNNT 126_ NVHLK 131_ LVNPL 136_ RHGII 141_ VDWDT 146_ VQDIW 151_ EYLFR 156_ QEMKI 161_ APEEH 166_ AVLVS 171_ DPPLS 176_ PHTNR 181_ EKYAE 186_ MLFEA 191_ FNTPA 196_ MHIAY 201_ QSRLS 206_ MYSYG 211_ RTSGL 216_ VVEVG 221_ HGVSY 226_ VVPIY 231_ EGYPL 236_ PSITG 241_ RLDYA 246_ GSDLT 251_ AYLLG 256_ LLNSA 261_ GNEFT 266_ QDQMG 271_ IVEDI 276_ KKKCC 281_ FVALD 286_ PIEEK 291_ KVPLS 296_ EHTIR 301_ YVLPD 306_ GKEIQ 311_ LCQER 316_ FLCSE 321_ MFFKP 326_ SLIKS 331_ MQLGL 336_ HTQTV 341_ SCLNK 346_ CDIAL 351_ KRDLM 356_ GNILL 361_ CGGST 366_ MLSGF 371_ PNRLQ 376_ KELSS 381_ MCPND 386_ TPQVN 391_ VLPER 396_ DSAVW 401_ TGGSI 406_ LASLQ 411_ GFQPL 416_ WVHRF 421_ EYEEH 426_GPFFL

Protein annotations

Protein functions:

1: Essential for normal spermatogenesis and male fertility. Required for normal sperm head morphology, acroplaxome formation, acrosome attachment, and acrosome granule stability. May anchor and stabilize acrosomal adherence to the acroplaxome at least in part by facilitating the presence of F-actin in the subacrosomal space (By similarity). May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis (PubMed:32923619)