Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B)
1_MGQRL 6_ SGGRS 11_ CLDVP 16_ GRLLP 21_ QPPPP 26_ PPPVR 31_ RKLAL 36_ LFAML 41_ CVWLY 46_ MFLYS 51_ CAGSC 56_ AAAPG 61_ LLLLG 66_ SGSRA 71_ AHDPP 76_ ALATA 81_ PDGTP 86_ PRLPF 91_ RAPPA 96_ TPLAS 101_ GKEMA 106_ EGAAS 111_ PEEQS 116_ PEVPD 121_ SPSPI 126_ SSFFS 131_ GSGSK 136_ QLPQA 141_ IIIGV 146_ KKGGT 151_ RALLE 156_ FLRVH 161_ PDVRA 166_ VGAEP 171_ HFFDR 176_ SYDKG 181_ LAWYR 186_ DLMPR 191_ TLDGQ 196_ ITMEK 201_ TPSYF 206_ VTREA 211_ PARIS 216_ AMSKD 221_ TKLIV 226_ VVRDP 231_ VTRAI 236_ SDYTQ 241_ TLSKR 246_ PDIPT 251_ FESLT 256_ FKNRT 261_ AGLID 266_ TSWSA 271_ IQIGI 276_ YAKHL 281_ EHWLR 286_ HFPIR 291_ QMLFV 296_ SGERL 301_ ISDPA 306_ GELGR 311_ VQDFL 316_ GLKRI 321_ ITDKH 326_ FYFNK 331_ TKGFP 336_ CLKKA 341_ EGSSR 346_ PHCLG 351_ KTKGR 356_ THPEI 361_ DREVV 366_ RRLRE 371_ FYRPF 376_ NLKFY 381_QMTGH
1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate (PubMed:10520990, PubMed:9988768). Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2 (PubMed:10520990, PubMed:9988768). The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry (PubMed:10520990). Unlike HS3ST1/3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate (PubMed:9988768)