Voltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit) (Transmembrane AMPAR regulatory protein gamma-2) (TARP gamma-2)
1_MGLFD 6_ RGVQM 11_ LLTTV 16_ GAFAA 21_ FSLMT 26_ IAVGT 31_ DYWLY 36_ SRGVC 41_ KTKSV 46_ SENET 51_ SKKNE 56_ EVMTH 61_ SGLWR 66_ TCCLE 71_ GNFKG 76_ LCKQI 81_ DHFPE 86_ DADYE 91_ ADTAE 96_ YFLRA 101_ VRASS 106_ IFPIL 111_ SVILL 116_ FMGGL 121_ CIAAS 126_ EFYKT 131_ RHNII 136_ LSAGI 141_ FFVSA 146_ GLSNI 151_ IGIIV 156_ YISAN 161_ AGDPS 166_ KSDSK 171_ KNSYS 176_ YGWSF 181_ YFGAL 186_ SFIIA 191_ EMVGV 196_ LAVHM 201_ FIDRH 206_ KQLRA 211_ TARAT 216_ DYLQA 221_ SAITR 226_ IPSYR 231_ YRYQR 236_ RSRSS 241_ SRSTE 246_ PSHSR 251_ DASPV 256_ GIKGF 261_ NTLPS 266_ TEISM 271_ YTLSR 276_ DPLKA 281_ ATTPT 286_ ATYNS 291_ DRDNS 296_ FLQVH 301_ NCIQK 306_ ENKDS 311_ LHSNT 316_ANRRT
1: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state