Transforming acidic coiled-coil-containing protein 3 (ERIC-1)
1_MSLQV 6_ LNDKN 11_ VSNEK 16_ NTENC 21_ DFLFS 26_ PPEVT 31_ GRSSV 36_ LRVSQ 41_ KENVP 46_ PKNLA 51_ KAMKV 56_ TFQTP 61_ LRDPQ 66_ THRIL 71_ SPSMA 76_ SKLEA 81_ PFTQD 86_ DTLGL 91_ ENSHP 96_ VWTQK 101_ ENQQL 106_ IKEVD 111_ AKTTH 116_ GILQK 121_ PVEAD 126_ TDLLG 131_ DASPA 136_ FGSGS 141_ SSESG 146_ PGALA 151_ DLDCS 156_ SSSQS 161_ PGSSE 166_ NQMVS 171_ PGKVS 176_ GSPEQ 181_ AVEEN 186_ LSSYS 191_ LDRRV 196_ TPASE 201_ TLEDP 206_ CRTES 211_ QHKAE 216_ TPHGA 221_ EEECK 226_ AETPH 231_ GAEEE 236_ CRHGG 241_ VCAPA 246_ AVATS 251_ PPGAI 256_ PKEAC 261_ GGAPL 266_ QGLPG 271_ EALGC 276_ PAGVG 281_ TPVPA 286_ DGTQT 291_ LTCAH 296_ TSAPE 301_ STAPT 306_ NHLVA 311_ GRAMT 316_ LSPQE 321_ EVAAG 326_ QMASS 331_ SRSGP 336_ VKLEF 341_ DVSDG 346_ ATSKR 351_ APPPR 356_ RLGER 361_ SGLKP 366_ PLRKA 371_ AVRQQ 376_ KAPQE 381_ VEEDD 386_ GRSGA 391_ GEDPP 396_ MPASR 401_ GSYHL 406_ DWDKM 411_ DDPNF 416_ IPFGG 421_ DTKSG 426_ CSEAQ 431_ PPESP 436_ ETRLG 441_ QPAAE 446_ QLHAG 451_ PATEE 456_ PGPCL 461_ SQQLH 466_ SASAE 471_ DTPVV 476_ QLAAE 481_ TPTAE 486_ SKERA 491_ LNSAS 496_ TSLPT 501_ SCPGS 506_ EPVPT 511_ HQQGQ 516_ PALEL 521_ KEESF 526_ RDPAE 531_ VLGTG 536_ AEVDY 541_ LEQFG 546_ TSSFK 551_ ESALR 556_ KQSLY 561_ LKFDP 566_ LLRDS 571_ PGRPV 576_ PVATE 581_ TSSMH 586_ GANET 591_ PSGRP 596_ REAKL 601_ VEFDF 606_ LGALD 611_ IPVPG 616_ PPPGV 621_ PAPGG 626_ PPLST 631_ GPIVD 636_ LLQYS 641_ QKDLD 646_ AVVKA 651_ TQEEN 656_ RELRS 661_ RCEEL 666_ HGKNL 671_ ELGKI 676_ MDRFE 681_ EVVYQ 686_ AMEEV 691_ QKQKE 696_ LSKAE 701_ IQKVL 706_ KEKDQ 711_ LTTDL 716_ NSMEK 721_ SFSDL 726_ FKRFE 731_ KQKEV 736_ IEGYR 741_ KNEES 746_ LKKCV 751_ EDYLA 756_ RITQE 761_ GQRYQ 766_ ALKAH 771_ AEEKL 776_ QLANE 781_ EIAQV 786_ RSKAQ 791_ AEALA 796_ LQASL 801_ RKEQM 806_ RIQSL 811_ EKTVE 816_ QKTKE 821_ NEELT 826_ RICDD 831_LISKM
1: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as a component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825). May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476)