Protein Wnt-6
1_MLPPL 6_ PSRLG 11_ LLLLL 16_ LLCPA 21_ HVGGL 26_ WWAVG 31_ SPLVM 36_ DPTSI 41_ CRKAR 46_ RLAGR 51_ QAELC 56_ QAEPE 61_ VVAEL 66_ ARGAR 71_ LGVRE 76_ CQFQF 81_ RFRRW 86_ NCSSH 91_ SKAFG 96_ RILQQ 101_ DIRET 106_ AFVFA 111_ ITAAG 116_ ASHAV 121_ TQACS 126_ MGELL 131_ QCGCQ 136_ APRGR 141_ APPRP 146_ SGLPG 151_ TPGPP 156_ GPAGS 161_ PEGSA 166_ AWEWG 171_ GCGDD 176_ VDFGD 181_ EKSRL 186_ FMDAR 191_ HKRGR 196_ GDIRA 201_ LVQLH 206_ NNEAG 211_ RLAVR 216_ SHTRT 221_ ECKCH 226_ GLSGS 231_ CALRT 236_ CWQKL 241_ PPFRE 246_ VGARL 251_ LERFH 256_ GASRV 261_ MGTND 266_ GKALL 271_ PAVRT 276_ LKPPG 281_ RADLL 286_ YAADS 291_ PDFCA 296_ PNRRT 301_ GSPGT 306_ RGRAC 311_ NSSAP 316_ DLSGC 321_ DLLCC 326_ GRGHR 331_ QESVQ 336_ LEENC 341_ LCRFH 346_ WCCVV 351_ QCHRC 356_RVRKE
1: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway