COMM domain-containing protein 10
1_MAVPA 6_ ALILR 11_ ESPSM 16_ KKAVS 21_ LINAI 26_ DTGRF 31_ PRLLT 36_ RILQK 41_ LHLKA 46_ ESSFS 51_ EEEEE 56_ KLQAA 61_ FSLEK 66_ QDLHL 71_ VLETI 76_ SFILE 81_ QAVYH 86_ NVKPA 91_ ALQQQ 96_ LENIH 101_ LRQDK 106_ AEAFV 111_ NTWSS 116_ MGQET 121_ VEKFR 126_ QRILA 131_ PCKLE 136_ TVGWQ 141_ LNLQM 146_ AHSAQ 151_ AKLKS 156_ PQAVL 161_ QLGVN 166_ NEDSK 171_ SLEKV 176_ LVEFS 181_ HKELF 186_ DFYNK 191_ LETIQ 196_AQLDS
1: Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (PubMed:37172566, PubMed:38459129). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966)