Gap junction alpha-3 protein (Connexin-46) (Cx46)
1_MGDWS 6_ FLGRL 11_ LENAQ 16_ EHSTV 21_ IGKVW 26_ LTVLF 31_ IFRIL 36_ VLGAA 41_ AEDVW 46_ GDEQS 51_ DFTCN 56_ TQQPG 61_ CENVC 66_ YDRAF 71_ PISHI 76_ RFWAL 81_ QIIFV 86_ STPTL 91_ IYLGH 96_ VLHIV 101_ RMEEK 106_ KKERE 111_ EEEQL 116_ KRESP 121_ SPKEP 126_ PQDNP 131_ SSRDD 136_ RGRVR 141_ MAGAL 146_ LRTYV 151_ FNIIF 156_ KTLFE 161_ VGFIA 166_ GQYFL 171_ YGFEL 176_ KPLYR 181_ CDRWP 186_ CPNTV 191_ DCFIS 196_ RPTEK 201_ TIFII 206_ FMLAV 211_ ACASL 216_ LLNML 221_ EIYHL 226_ GWKKL 231_ KQGVT 236_ SRLGP 241_ DASEA 246_ PLGTA 251_ DPPPL 256_ PPSSR 261_ PPAVA 266_ IGFPP 271_ YYAHT 276_ AAPLG 281_ QARAV 286_ GYPGA 291_ PPPAA 296_ DFKLL 301_ ALTEA 306_ RGKGQ 311_ SAKLY 316_ NGHHH 321_ LLMTE 326_ QNWAN 331_ QAAER 336_ QPPAL 341_ KAYPA 346_ ASTPA 351_ APSPV 356_ GSSSP 361_ PLAHE 366_ AEAGA 371_ APLLL 376_ DGSGS 381_ SLEGS 386_ ALAGT 391_ PEEEE 396_ QAVTT 401_ AAQMH 406_ QPPLP 411_ LGDPG 416_ RASKA 421_ SRASS 426_GRARP
1: Structural component of lens fiber gap junctions (PubMed:30044662). Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells (By similarity). They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (PubMed:30044662)